Lena Serrander, Klinisk mikrobiologi

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Article - Review (1)

1. Leukocyte endothelial cell interactions in pig to human organ xenograft rejection.

   Holgersson Jan, Ehrnfelt Cecilia, Hauzenberger Elenor, Serrander Lena.

   Vet Immunol Immunopathol. 2002:87(3):407-15.

   [Links: PMID: 12072266][Source: PubMed®]

   Web of Science® citations 10

Article - Peer reviewed scientific (18)

1. Activation of phospholipase D is an early event in integrin-mediated signalling leading to phagocytosis in human neutrophils.

   Serrander L, Fällman M, Stendahl O.

   Inflammation 1996:20(4):439-50.

   [Links: PMID: 8872506][Source: PubMed®]

   Web of Science® citations 33
2. Store-operated Ca2+ influx and stimulation of exocytosis in HL-60 granulocytes.

   Nüsse O, Serrander L, Foyouzi-Youssefi R, Monod A, Lew D P, Krause K H.

   J Biol Chem. 1997:272(45):28360-7.

   [Links: PMID: 9353293][Source: PubMed®]

   Web of Science® citations 29
3. Ca2+-induced exocytosis in individual human neutrophils: high- and low-affinity granule populations and submaximal responses.

   Nüsse O, Serrander L, Lew D P, Krause K H.

   EMBO J. 1998:17(5):1279-88.

   [Links: PMID: 9482725 | DOI länk][Source: PubMed®]

   Web of Science® citations 47
4. Electron currents generated by the human phagocyte NADPH oxidase.

   Schrenzel J, Serrander L, Bánfi B, Nüsse O, Fouyouzi R, Lew D P, Demaurex N, Krause K H.

   Nature 1998:392(6677):734-7.

   [Links: PMID: 9565037 | DOI länk][Source: PubMed®]

   Web of Science® citations 107
5. CR3, FcgammaRIIA and FcgammaRIIIB induce activation of the respiratory burst in human neutrophils: the role of intracellular Ca(2+), phospholipase D and tyrosine phosphorylation.

   Löfgren R, Serrander L, Forsberg M, Wilsson A, Wasteson A, Stendahl O.

   Biochim Biophys Acta 1999:1452(1):46-59.

   [Links: PMID: 10525159][Source: PubMed®]

   Web of Science® citations 36
6. Particles binding beta(2)-integrins mediate intracellular production of oxidative metabolites in human neutrophils independently of phagocytosis.

   Serrander L, Larsson J, Lundqvist H, Lindmark M, Fällman M, Dahlgren C, Stendahl O.

   Biochim Biophys Acta 1999:1452(2):133-44.

   [Links: PMID: 10559466][Source: PubMed®]

   Web of Science® citations 28
7. Selective inhibition of IgG-mediated phagocytosis in gelsolin-deficient murine neutrophils.

   Serrander L, Skarman P, Rasmussen B, Witke W, Lew D P, Krause K H, Stendahl O, Nüsse O.

   J Immunol. 2000:165(5):2451-7.

   [Links: PMID: 10946270][Source: PubMed®]

   Web of Science® citations 44
8. Involvement of the beta2-integrin CD18 in apoptosis signal transduction in human neutrophils.

   Larsson J, Serrander L, Stendahl O, Lundqvist-Gustafsson H.

   Inflamm Res. 2000:49(9):452-9.

   [Links: PMID: 11071119][Source: PubMed®]

   Web of Science® citations 9
9. Synaptotagmin II could confer Ca(2+) sensitivity to phagocytosis in human neutrophils.

   Lindmark I Maria, Karlsson Anna, Serrander Lena, Francois Patrice, Lew Daniel, Rasmusson Birgitta, Stendahl Olle, Nüsse Oliver.

   Biochim Biophys Acta 2002:1590(1):159-66.

   [Links: PMID: 12063179][Source: PubMed®]

   Web of Science® citations 13
10. Porcine endothelium activated by anti-alpha-GAL antibody binding mediates increased human neutrophil adhesion under flow.

    Ehrnfelt Cecilia, Serrander Lena, Holgersson Jan.

    Transplantation 2003:76(7):1112-9.

    [Links: PMID: 14557762 | DOI länk][Source: PubMed®]

    Web of Science® citations 19
11. T cell contact-mediated activation of respiratory burst in human polymorphonuclear leukocytes is inhibited by high-density lipoproteins and involves CD18.

    Cettour-Rose Philippe, Nguyen Thi Xuan Khanh, Serrander Lena, Kaufmann Marie-Thérèse, Dayer Jean-Michel, Burger Danielle, Roux-Lombard Pascale.

    J Leukoc Biol 2005:77(1)

    [Links: PMID: 15498815][Source: PubMed®]

    Web of Science® citations 11
12. Expression and activity of NOX5 in the circulating malignant B cells of hairy cell leukemia.

    Kamiguti Aura S, Serrander Lena, Lin Ke, Harris Robert J, Cawley John C, Allsup David J, Slupsky Joseph R, Krause Karl-Heinz, Zuzel Mirko.

    J Immunol. 2005:175(12):8424-30.

    [Links: PMID: 16339585][Source: PubMed®]

    Web of Science® citations 41
13. A key role for the microglial NADPH oxidase in APP-dependent killing of neurons.

    Qin Bin, Cartier Laetitia, Dubois-Dauphin Michel, Li Bin, Serrander Lena.

    Neurobiol Aging 2006:(11)

    [Links: PMID: 16260066][Source: PubMed®]

    Web of Science® citations 27
14. The NADPH oxidase NOX4 drives cardiac differentiation: Role in regulating cardiac transcription factors and MAP kinase activation.

    Li Jian, Stouffs Michael, Serrander Lena, Banfi Botond, Bettiol Esther, Charnay Yves, Steger Klaus, Krause Karl-Heinz, Jaconi Marisa E.

    Mol Biol Cell 2006:17(9):3978-88.

    [Links: PMID: 16775014 | DOI länk][Source: PubMed®]

    Web of Science® citations 77
15. NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

    Serrander Lena, Cartier Laetitia, Bedard Karen, Banfi Botond, Lardy Bernard, Plastre Olivier, Sienkiewicz Andrzej, Fórró Lászlo, Schlegel Werner, Krause Karl-Heinz.

    Biochem J. 2007:406(1):105-14.

    [Links: PMID: 17501721 | DOI länk][Source: PubMed®]

    Web of Science® citations 129
16. NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation.

    Serrander Lena, Jaquet Vincent, Bedard Karen, Plastre Olivier, Hartley Oliver, Arnaudeau Serge, Demaurex Nicolas, Schlegel Werner, Krause Karl-Heinz.

    Biochimie 2007:89(9):1159-67.

    [Links: PMID: 17587483 | DOI länk][Source: PubMed®]

    Web of Science® citations 41
17. [Archeological laboratory results or microbiology of the time?]

    Sundqvist Martin, Schön Thomas, Serrander Lena.

    Lakartidningen 2011:108(15):844-5.

    [Links: PMID: 21674971][Source: PubMed®]
18. Real-time PCR detection of Human Herpesvirus 1-5 in patients lacking clinical signs of a viral CNS infection.

    Sundén Birgitta, Larsson Marie, Falkeborn Tina, Paues Jakob, Forsum Urban, Lindh Magnus, Ydrenius Liselotte, Akerlind Britt, Serrander Lena.

    BMC Infect Dis. 2011:11:220.

    [Links: PMID: 21849074 | DOI länk][Source: PubMed®]

    Web of Science® citations 0

Book Chapter (1)

1. Methods for Studying Calcium Control of Secretion.

   Nüsse Oliver, Serrander Lena, Krause Karl-Heinz.

   Calcium Signaling. Boca Raton, FL: CRC Press; 2000, pp 365-390.

   [Source: User]

Manuskript ännu ej accepterade för publikation

Arbetsgivare	Anställningsgrad		Började	Slutade
Statligt - Universitet - Linköpings universitet - Hälsouniversitetet		100%	1992	1992
		25%	1993	1995
Statligt - Övrigt - Övrigt Show info Geneves universitet, medicinsk fakultet		100%	1996	1999
Landsting - Stockholms läns landsting - Alla områden Show info Forskar AT med 18 mån klinik och 6 månader forskning		70%	1999	2001
Statligt - Universitet - Karolinska Institutet, Stockholm - Institutionen för medicin, Huddinge		30%	1999	2001
Statligt - Övrigt - Övrigt Show info Universitet i Geneve Medicinsk fakultet		100%	2002	2007
Landsting - Landstinget i Östergötland - Specialiserad vård - Laboratoriemedicinskt centrum		100%	2007

During 1992-1995, teaching consisted around 50% of the activity for medical students during their 2nd and 10th semester in medical microbiology in an PBL format, consisting in design and supervision of laboratory elements in immunology and microbiology.
I have been an PBL tutor for 3rd year medical students in Infectious Diseases, University of Geneva (27th of March -19th of May, 2006).
I am a co-supervisor for Michael Stouffs, a PhD student in the group of Marisa Jaconi, Faculty of Medicine of Geneva, planned to finish his thesis 2009.
From the 20th of March, I am co-supervising Michaela Nordvall and Dennis Blick from the Biology program, Linköping in their diploma projects together with Per-Erik Lindgren, Medical Microbiology, Linköping. Michaela finished and presented her diploma in january 2008.
I frequently give presentations/lectures (local, national and international) since I started my position in clinical microbiology on topics as molecular methods, free radicals, host-pathogen interactions.
I am secretary in a forum (ST-råd)aimed to improve the education for specializing young doctors in the county of Östergötland.Facklig representant för läkarförbundet på klinisk mikrobiologi, DC, LiÖ.
Utveckling av molekylär diagnostik framförallt inom virologi, men även inom bakteriologi.

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