personkort Maria Jenmalm, IKE / AIR, Hälsouniversitetet i Linköping

Basuppgifter

namn:
Maria Jenmalm
arbetsplats:
IKE / AIR, Hälsouniversitetet i Linköping
yrkestitel:
Professor
e-post

Arbete

arbetsplats:
IKE / AIR, Hälsouniversitetet i Linköping
telefon:
010 103 41 01
arbetsgivarkategori:
Universitet/Högskola
adress:
AIR plan 10
postadress:
581 85 Linköping
land:
Sverige

CV

Article - Peer reviewed scientific (53)

  1. Synergistic inhibition of thrombin-induced platelet aggregation by the novel nitric oxide-donor GEA 3175 and adenosine.
    Grenegård M, Gustafsson M C, Andersson R G, Bengtsson T.
    Br J Pharmacol. 1996:118(8):2140-4.
    [Links: PMID: 8864553][Source: PubMed®]
    Web of Science® citations 12
  2. Maternal influence on IgG subclass antibodies to Bet v 1 during the first 18 months of life as detected with a sensitive ELISA.
    Jenmalm M C, Holt P G, Björkstén B.
    Int Arch Allergy Immunol. 1997:114(2):175-84.
    [Links: PMID: 9338612][Source: PubMed®]
    Web of Science® citations 27
  3. Exposure to cow's milk during the first 3 months of life is associated with increased levels of IgG subclass antibodies to beta-lactoglobulin to 8 years.
    Jenmalm M C, Björkstén B.
    J Allergy Clin Immunol. 1998:102(4):671-8.
    [Links: PMID: 9802378][Source: PubMed®]
    Web of Science® citations 32
  4. Cow's milk IgE and IgG antibody responses to cow's milk formulas.
    Oldaeus G, Björkstén B, Jenmalm M C, Kjellman N I.
    Allergy 1999:54(4):352-7.
    [Links: PMID: 10371094][Source: PubMed®]
    Web of Science® citations 15
  5. Regulation of T-helper cell responses to inhalant allergen during early childhood.
    Macaubas C, Sly P D, Burton P, Tiller K, Yabuhara A, Holt B J, Smallacombe T B, Kendall G, Jenmalm M C, Holt P G.
    Clin Exp Allergy 1999:29(9):1223-31.
    [Links: PMID: 10469031][Source: PubMed®]
    Web of Science® citations 87
  6. Development of immunoglobulin G subclass antibodies to ovalbumin, birch and cat during the first eight years of life in atopic and non-atopic children.
    Jenmalm M C, Björkstén B.
    Pediatr Allergy Immunol 1999:10(2):112-21.
    [Links: PMID: 10478613][Source: PubMed®]
    Web of Science® citations 23
  7. Allergen-induced cytokine secretion in relation to atopic symptoms and immunoglobulin E and immunoglobulin G subclass antibody responses.
    Jenmalm M C, Björkstén B, Macaubas C, Holt B J, Smallacombe T B, Holt P G.
    Pediatr Allergy Immunol 1999:10(3):168-77.
    [Links: PMID: 10565557][Source: PubMed®]
    Web of Science® citations 30
  8. Cord blood levels of immunoglobulin G subclass antibodies to food and inhalant allergens in relation to maternal atopy and the development of atopic disease during the first 8 years of life.
    Jenmalm M C, Björkstén B.
    Clin Exp Allergy 2000:30(1):34-40.
    [Links: PMID: 10606928][Source: PubMed®]
    Web of Science® citations 30
  9. Cytokines in breast milk from allergic and nonallergic mothers.
    Böttcher M F, Jenmalm M C, Garofalo R P, Björkstén B.
    Pediatr Res. 2000:47(1):157-62.
    [Links: PMID: 10625097][Source: PubMed®]
    Web of Science® citations 90
  10. Chemoattractant factors in breast milk from allergic and nonallergic mothers.
    Böttcher M F, Jenmalm M C, Björkstén B, Garofalo R P.
    Pediatr Res. 2000:47(5):592-7.
    [Links: PMID: 10813582][Source: PubMed®]
    Web of Science® citations 49
  11. Effects of maternal allergen-specific IgG in cord blood on early postnatal development of allergen-specific T-cell immunity.
    Prescott S L, Holt P G, Jenmalm M, Björkstén B.
    Allergy 2000:55(5):470-5.
    [Links: PMID: 10843428][Source: PubMed®]
    Web of Science® citations 34
  12. Expression of and responses to CD2 and CD3 in 18-month-old children with and without atopic dermatitis.
    Jenmalm M C, Aniansson-Zdolsek H, Holt P G, Björkstén B.
    Pediatr Allergy Immunol 2000:11(3):175-82.
    [Links: PMID: 10981527][Source: PubMed®]
    Web of Science® citations 7
  13. PHA-induced IL-12R beta(2) mRNA expression in atopic and non-atopic children.
    Janefjord C K, Jenmalm M C.
    Clin Exp Allergy 2001:31(10):1493-500.
    [Links: PMID: 11678847][Source: PubMed®]
    Web of Science® citations 12
  14. Allergen-induced Th1 and Th2 cytokine secretion in relation to specific allergen sensitization and atopic symptoms in children.
    Jenmalm M C, Van Snick J, Cormont F, Salman B.
    Clin Exp Allergy 2001:31(10):1528-35.
    [Links: PMID: 11678852][Source: PubMed®]
    Web of Science® citations 42
  15. Detection of spontaneous and antigen-induced human interleukin-4 responses in vitro: comparison of ELISPOT, a novel ELISA and real-time RT-PCR.
    Ekerfelt Christina, Ernerudh Jan, Jenmalm Maria C.
    J Immunol Methods 2002:260(1):55-67.
    [Links: PMID: 11792376][Source: PubMed®]
    Web of Science® citations 51
  16. Total and allergen-specific immunoglobulin A levels in saliva in relation to the development of allergy in infants up to 2 years of age.
    Böttcher M F, Häggström P, Björkstén B, Jenmalm M C.
    Clin Exp Allergy 2002:32(9):1293-8.
    [Links: PMID: 12220466][Source: PubMed®]
    Web of Science® citations 43
  17. Effect of heat denaturation on beta-lactoglobulin-induced gastrointestinal sensitization in rats: denatured betaLG induces a more intensive local immunologic response than native betaLG.
    Rytkönen Jani, Karttunen Tuomo J, Karttunen Riitta, Valkonen Kaija H, Jenmalm Maria C, Alatossava Tapani, Björkstén Bengt, Kokkonen Jorma.
    Pediatr Allergy Immunol 2002:13(4):269-77.
    [Links: PMID: 12390443][Source: PubMed®]
    Web of Science® citations 14
  18. Immune responses to birch in young children during their first 7 years of life.
    Böttcher M F, Jenmalm M C, Björkstén B.
    Clin Exp Allergy 2002:32(12):1690-8.
    [Links: PMID: 12653157][Source: PubMed®]
    Web of Science® citations 18
  19. Effects of breast milk from allergic and non-allergic mothers on mitogen- and allergen-induced cytokine production.
    Böttcher Malin F, Fredriksson Jenny, Hellquist Anna, Jenmalm Maria C.
    Pediatr Allergy Immunol 2003:14(1):27-34.
    [Links: PMID: 12603708][Source: PubMed®]
    Web of Science® citations 9
  20. Cytokine, chemokine and secretory IgA levels in human milk in relation to atopic disease and IgA production in infants.
    Böttcher Malin F, Jenmalm Maria C, Björkstén Bengt.
    Pediatr Allergy Immunol 2003:14(1):35-41.
    [Links: PMID: 12603709][Source: PubMed®]
    Web of Science® citations 39
  21. Endotoxin levels in Estonian and Swedish house dust and atopy in infancy.
    Böttcher M F, Björkstén B, Gustafson S, Voor T, Jenmalm M C.
    Clin Exp Allergy 2003:33(3):295-300.
    [Links: PMID: 12614441][Source: PubMed®]
    Web of Science® citations 60
  22. Expression of the T-cell markers CD2 and CD28 in healthy and atopic children during the first 18 months of life.
    Zdolsek Helena A, Jenmalm Maria C.
    Pediatr Allergy Immunol 2003:14(3):169-77.
    [Links: PMID: 12787295][Source: PubMed®]
    Web of Science® citations 4
  23. Asthma, lung function and allergy in 12-year-old children with very low birth weight: a prospective study.
    Mai Xiao-Mei, Gäddlin Per-Olof, Nilsson Lennart, Finnström Orvar, Björkstén Bengt, Jenmalm Maria C, Leijon Ingemar.
    Pediatr Allergy Immunol 2003:14(3):184-92.
    [Links: PMID: 12787297][Source: PubMed®]
    Web of Science® citations 34
  24. Characterization of the CD200 receptor family in mice and humans and their interactions with CD200.
    Wright Gavin J, Cherwinski Holly, Foster-Cuevas Mildred, Brooke Gary, Puklavec Michael J, Bigler Mike, Song Yaoli, Jenmalm Maria, Gorman Dan, McClanahan Terri, Liu Man-Ru, Brown Marion H, Sedgwick Jonathon D, Phillips Joseph H, Barclay A Neil.
    J Immunol. 2003:171(6):3034-46.
    [Links: PMID: 12960329][Source: PubMed®]
    Web of Science® citations 134
  25. Allergen-induced cytokine secretion in atopic and non-atopic asthmatic children.
    Böttcher Malin F, Bjurström Jenny, Mai Xiao-Mei, Nilsson Lennart, Jenmalm Maria C.
    Pediatr Allergy Immunol 2003:14(5):345-50.
    [Links: PMID: 14641603][Source: PubMed®]
    Web of Science® citations 14
  26. Reduced IL-2-induced IL-12 responsiveness in atopic children.
    Aniansson Zdolsek Helena, Janefjord Camilla K, Fälth-Magnusson Karin, Jenmalm Maria C.
    Pediatr Allergy Immunol 2003:14(5):351-7.
    [Links: PMID: 14641604][Source: PubMed®]
  27. Reduced levels of soluble CD14 in atopic children.
    Zdolsek H A, Jenmalm M C.
    Clin Exp Allergy 2004:34(4):532-9.
    [Links: PMID: 15080804 | DOI länk][Source: PubMed®]
    Web of Science® citations 26
  28. Cat allergen-induced cytokine secretion and Fel d 1-immunoglobulin G immune complexes in cord blood.
    Casas R, Jenmalm M C, Björkstén B.
    Clin Exp Allergy 2004:34(4):591-6.
    [Links: PMID: 15080812 | DOI länk][Source: PubMed®]
    Web of Science® citations 4
  29. Effect of cryopreservation on expression of Th1 and Th2 cytokines in blood mononuclear cells from patients with different cytokine profiles, analysed with three common assays: an overall decrease of interleukin-4.
    Kvarnström M, Jenmalm M C, Ekerfelt C.
    Cryobiology 2004:49(2):157-68.
    [Links: PMID: 15351687 | DOI länk][Source: PubMed®]
  30. A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children.
    Fagerås Böttcher Malin, Hmani-Aifa Mounira, Lindström Anna, Jenmalm Maria Christina, Mai Xiao-Mei, Nilsson Lennart, Zdolsek Helena Aniansson, Björkstén Bengt, Söderkvist Peter, Vaarala Outi.
    J Allergy Clin Immunol. 2004:114(3):561-7.
    [Links: PMID: 15356557 | DOI länk][Source: PubMed®]
  31. Atopic sensitization and atopic dermatitis in Estonian and Swedish infants.
    Voor T, Julge K, Böttcher M F, Jenmalm M C, Duchén K, Björkstén B.
    Clin Exp Allergy 2005:35(2):153-9.
    [Links: PMID: 15725185 | DOI länk][Source: PubMed®]
    Web of Science® citations 17
  32. Regulation of myeloid cell function through the CD200 receptor.
    Jenmalm Maria C, Cherwinski Holly, Bowman Edward P, Phillips Joseph H, Sedgwick Jonathon D.
    J Immunol. 2006:176(1):191-9.
    [Links: PMID: 16365410][Source: PubMed®]
    Web of Science® citations 50
  33. Cytokine responses to allergens during the first 2 years of life in Estonian and Swedish children.
    Böttcher M F, Jenmalm M C, Voor T, Julge K, Holt P G, Björkstén B.
    Clin Exp Allergy 2006:36(5):619-28.
    [Links: PMID: 16650047 | DOI länk][Source: PubMed®]
    Web of Science® citations 8
  34. Decreased up-regulation of the interleukin-12Rbeta2-chain and interferon-gamma secretion and increased number of forkhead box P3-expressing cells in patients with a history of chronic Lyme borreliosis compared with asymptomatic Borrelia-exposed indiv.
    Jarefors S, Janefjord C K, Forsberg P, Jenmalm M C, Ekerfelt C.
    Clin Exp Immunol. 2007:147(1):18-27.
    [Links: PMID: 17177959 | DOI länk][Source: PubMed®]
    Web of Science® citations 8
  35. Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trial.
    Abrahamsson Thomas R, Jakobsson Ted, Böttcher Malin Fagerås, Fredrikson Mats, Jenmalm Maria C, Björkstén Bengt, Oldaeus Göran.
    J Allergy Clin Immunol. 2007:119(5):1174-80.
    [Links: PMID: 17349686 | DOI länk][Source: PubMed®]
    Web of Science® citations 121
  36. Monoclonal antibody-mediated CD200 receptor signaling suppresses macrophage activation and tissue damage in experimental autoimmune uveoretinitis.
    Copland David A, Calder Claudia J, Raveney Ben J E, Nicholson Lindsay B, Phillips Joseph, Cherwinski Holly, Jenmalm Maria, Sedgwick Jonathon D, Dick Andrew D.
    Am J Pathol. 2007:171(2):580-8.
    [Links: PMID: 17600119 | DOI länk][Source: PubMed®]
    Web of Science® citations 36
  37. High levels of IgG(4) antibodies to foods during infancy are associated with tolerance to corresponding foods later in life.
    Tomici Sara, Norrman Gunilla, Fälth-Magnusson Karin, Jenmalm Maria C, Devenney Irene, Böttcher Malin Fagerås.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2008
    [Links: PMID: 18346097 | DOI länk][Source: PubMed®]
    Web of Science® citations 17
  38. Increased circulating paternal antigen-specific IFN-gamma- and IL-4-secreting cells during pregnancy in allergic and non-allergic women.
    Persson Marie, Ekerfelt Christina, Ernerudh Jan, Matthiesen Leif, Jenmalm Maria, Jonsson Yvonne, Sandberg Martina, Berg Göran.
    J Reprod Immunol. 2008
    [Links: PMID: 18752853 | DOI länk][Source: PubMed®]
    Web of Science® citations 1
  39. Cord blood cytokines and chemokines and development of allergic disease.
    Sandberg Martina, Frykman Anne, Ernerudh Jan, Berg Göran, Matthiesen Leif, Ekerfelt Christina, Nilsson Lennart J, Jenmalm Maria C.
    Pediatr Allergy Immunol 2008
    [Links: PMID: 19175890 | DOI länk][Source: PubMed®]
    Web of Science® citations 13
  40. Altered early infant gut microbiota in children developing allergy up to 5 years of age.
    Sjögren Y M, Jenmalm M C, Böttcher M F, Björkstén B, Sverremark-Ekström E.
    Clin Exp Allergy 2009:39(4):518-26.
    [Links: PMID: 19220322 | DOI länk][Source: PubMed®]
    Web of Science® citations 40
  41. Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17{beta}-estradiol.
    Mjösberg Jenny, Svensson Judit, Johansson Emma, Hellström Lotta, Casas Rosaura, Jenmalm Maria C, Boij Roland, Matthiesen Leif, Jönsson Jan-Ingvar, Berg Göran, Ernerudh Jan.
    J Immunol. 2009:183(1):759-69.
    [Links: PMID: 19535629 | DOI länk][Source: PubMed®]
    Web of Science® citations 30
  42. Total and allergen-specific IgE levels during and after pregnancy in relation to maternal allergy.
    Sandberg Martina, Frykman Anne, Jonsson Yvonne, Persson Marie, Ernerudh Jan, Berg Göran, Matthiesen Leif, Ekerfelt Christina, Jenmalm Maria C.
    J Reprod Immunol. 2009:81(1):82-8.
    [Links: PMID: 19539377 | DOI länk][Source: PubMed®]
  43. Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responses.
    Sjögren Y M, Tomicic S, Lundberg A, Böttcher M F, Björkstén B, Sverremark-Ekström E, Jenmalm M C.
    Clin Exp Allergy 2009:39(12):1842-51.
    [Links: PMID: 19735274 | DOI länk][Source: PubMed®]
    Web of Science® citations 25
  44. Breast milk cytokine and IgA composition differ in Estonian and Swedish mothers - relationship to microbial pressure and infant allergy.
    Tomicic Sara, Johansson Git, Voor Tiia, Björkstén Bengt, Fagerås Malin, Jenmalm Maria.
    Pediatric Research 2010
    [Source: User]
  45. FOXP3+ regulatory T cells and T helper 1, T helper 2, and T helper 17 cells in human early pregnancy decidua.
    Mjösberg Jenny, Berg Göran, Jenmalm Maria C, Ernerudh Jan.
    Biol Reprod. 2010:82(4):698-705.
    [Links: PMID: 20018909 | DOI länk][Source: PubMed®]
  46. Transcriptional characteristics of CD4+ T cells in multiple sclerosis: relative lack of suppressive populations in blood.
    Edström M, Mellergård J, Mjösberg J, Jenmalm Mc, Vrethem M, Press R, Dahle C, Ernerudh J.
    Mult Scler. 2011:17(1):57-66.
    [Links: PMID: 20847001 | DOI länk][Source: PubMed®]
    Web of Science® citations 2
  47. Th1 and Th2 chemokines, vaccine-induced immunity, and allergic disease in infants after maternal .
    Furuhjelm Catrin, Jenmalm Maria C, Fälth-Magnusson Karin, Duchén Karel.
    Pediatr Res. 2011:69(3):259-64.
    [Links: PMID: 21099447 | DOI länk][Source: PubMed®]
    Web of Science® citations 1
  48. High salivary secretory IgA antibody levels are associated with less late-onset wheezing in IgE-sensitized infants.
    Sandin Anna, Björkstén Bengt, Böttcher Malin F, Englund Erling, Jenmalm Maria C, Bråbäck Lennart.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2011
    [Links: PMID: 21332801 | DOI länk][Source: PubMed®]
  49. Childhood immune maturation and allergy development: regulation by maternal immunity and microbial exposure.
    Jenmalm Maria C.
    Am J Reprod Immunol. 2011:66 Suppl 1:75-80.
    [Links: PMID: 21726341 | DOI länk][Source: PubMed®]
    Web of Science® citations 0
  50. High Cord Blood Levels of the T-Helper 2-Associated Chemokines CCL17 and CCL22 Precede Allergy Development During the First 6 Years of Life.
    Abelius Martina S, Ernerudh Jan, Berg Göran, Matthiesen Leif, Nilsson Lennart J, Jenmalm Maria C.
    Pediatr Res. 2011:70(5):495-500.
    [Links: PMID: 21796021 | DOI länk][Source: PubMed®]
    Web of Science® citations 2
  51. A Th1/Th2-associated chemokine imbalance during infancy in children developing eczema, wheeze and sensitization.
    Abrahamsson T R, Abelius M, Forsberg A, Björkstén B, Jenmalm M C.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011
    [Links: PMID: 21801246 | DOI länk][Source: PubMed®]
  52. Slow salivary secretory IgA maturation may relate to low microbial pressure and allergic symptoms in sensitized children.
    Fagerås Malin, Tomi Sara, Voor Tiia, Björkstén Bengt, Jenmalm Maria C.
    Pediatric research 2011
    [Links: PMID: 21857384 | DOI länk][Source: PubMed®]
  53. Macrophages at the Fetal-Maternal Interface Express Markers of Alternative Activation and Are Induced by M-CSF and IL-10.
    Svensson Judit, Jenmalm Maria C, Matussek Andreas, Geffers Robert, Berg Göran, Ernerudh Jan.
    Journal of immunology (Baltimore, Md : 1950) 2011
    [Links: PMID: 21890660 | DOI länk][Source: PubMed®]

Accepterade men ännu ej publicerade publikationer

Skogman BH, Hellberg S, Ekerfelt C, Jenmalm MC, Forsberg P, Ludvigsson J, Sven Bergström S, Ernerudh J: Adaptive and innate immune responsiveness to Borrelia burgdorferi sensu lato in exposed asymptomatic children and children with previous clinical Lyme Borreliosis. Clin Dev Immunol 2011; I tryck.

h-index 22 2011-10-10

information Nedan visas publikationer tillfälligt inlagda som text innan de konverteras till publikationsdatabasen.

Övriga publikationer

Översiktsartiklar

1. Jenmalm MC: Immune responses in early childhood in relation to the development of asthma. J Invest Allergol Clin Immunol 1997; 7: 306-308.

2. Kjellman NIM, Jenmalm MC, Nilsson L: Neonatal and perinatal factors for asthma and allergic diseases. Influence of month and place of birth. Progr Allergy Clin Immunol 1997; 4: 207-211.

3. Jenmalm MC, Björkstén B: Development of the immune system in atopic children. Pediatr Allergy Immunol 1998; 9: 5-12.

4. Jenmalm MC: Reduced T cell function in atopic children. Int Arch Allergy Immunol 1999; 118: 395-398.

5. Jenmalm MC: Role of infections in the immunological balance of infants. Cad Imun Alergol Ped 1999; 14: 78-79.

6. Böttcher MF, Jenmalm MC: Breast-feeding and the development of atopic disease during childhood. Clin Exp Allergy 2002; 32: 159-61.

7. Jenmalm MC: Childhood immune maturation and allergy development: Regulation by maternal immunity and microbial exposure. Am J Reprod Immunol 2011; I tryck.

Avhandling

Jenmalm MC: Development of IgG subclass antibodies to allergens in early childhood. Linköping Medical Dissertations 1999, No. 603.

Bokkapitel

Björkstén B, Jenmalm MC: Reglering av IgE-antikroppsbildningen [Regulation of IgE antibody synthesis]. In: Anniko M, Stierna P, Ställberg B, red. Övre luftvägarnas allergiska sjukdomar. Lund: Tika Läkemedel AB; 1999: 41-48.

Referee-granskade originalbidrag till vetenskapliga konferenser

1. Jenmalm MC. A sensitive ELISA to detect IgG subclass antibodies to Bet v 1 in infants. Int Arch Allergy Immunol 1997; 113: 252-254. CIA* 1996 Schloß Fuschl.

2. Jenmalm MC. IgG subclass antibodies to ovalbumin, birch and cat during the first 18 months of life. Allergy 1997; 52: 95. EAACI 1997 Rhodes.

3. Jenmalm MC. Immune responses in early childhood in relation to the development of asthma. J Invest Allergol Clin Immunol 1997; 7: 306-8. ESPACI 1997 Lisbon.

4. Jenmalm MC, Björkstén B. IgG subclass antibodies to egg, milk, birch and cat during the first 8 years of life in atopic and non-atopic children. Allergy Clin Immunol Int 1997; Suppl 4: 46. IAACI 1997 Cancún.

5. Kjellman NIM, Jenmalm MC, Nilsson L: Neonatal and perinatal factors for asthma and allergic diseases. Influence of month and place of birth. Progr Allergy Clin Immunol 1997; 4: 207-211. IAACI 1997 Cancún.

6. Jenmalm MC: Immune responses in early childhood in relation to the development of asthma. J Invest Allergol Clin Immunol 1997; 7: 306-8. Interasma 1997 Las Palmas.

7. Jenmalm MC, Julge K, Vasar M, Björkstén B. IgG subclass antibodies to egg, milk, cat and birch during the first two years of life in Estonian children. Allergy 1998; 53: 13. EAACI 1998 Birmingham.

8. Jenmalm MC. T cell function in atopic children. Int Arch Allergy Appl Immunol 1999; 118: 395-8. CIA 1998 Corfu.

9. Böttcher MF, Jenmalm MC, Björkstén B, Garofalo RP. Cytokines in breast milk from allergic and nonallergic mothers. Int Arch Allergy Immunol 1999; 118: 319-320. CIA 1998 Corfu.

10. Jenmalm MC, Björkstén B. Regulation of early immune responses to allergens. ESF ’Immunogenetics of Allergy: Towards Prevention and Care’ 1999 Berlin.

11. Jenmalm MC: Role of infections in the immunological balance of infants. Cad Imun Alergol Ped 1999; 14: 78-79. ESPACI Ponta Delgada 1999.

12. Jenmalm MC, Björkstén B, Macaubas C, Holt BJ, Smallacombe TB, Holt PG. Cord blood mononuclear cell cytokine responses to allergens. Allergy 1999; 54: 59. EAACI 1999 Brussels.

13. Jenmalm MC, Aniansson-Zdolsek H, Holt PG, Björkstén B. High IL-10 secretion in skin prick test negative children with atopic dermatitis. Genes Immunity 1999; 1: 78. IL-10 Workshop 1999 Milan.

14. Jenmalm MC, Macaubas C, Holt PG, Holt BJ, Smallacombe TB, Björkstén B. Allergen induced cytokine responses at birth in relation to development of atopic disease and sensitisation. J Allergy Clin Immunol 2000; 105: S110. AAAAI San Diego 2000.

15. Jenmalm MC. T cell response, IgE sensitisation and symptoms in infants. EAACI Lisbon 2000.

16. Böttcher MF, Jenmalm MC, Garofalo RP, Björkstén B. Chemoattractant factors in milk from allergic and non-allergic mothers. Allergy Clin Immunol Int 2000; 13: 91. WAO Sydney 2000.

17. Jenmalm MC, Björkstén B. Immune responses to birch during the first seven pollen seasons of life. Int Arch Allergy Immunol 2001; 124: 321-3. CIA Hakone 2000.

18. Böttcher MF, Jenmalm MC. The effects of breast milk on mitogen and allergen induced cytokine production from cord blood cells. J Allergy Clin Immunol 2001; 107: S78. AAAAI New Orleans 2001.

19. Böttcher MF, Jenmalm MC, Björkstén B. Cytokines and chemokines in breast milk in relation to the development of allergy and IgA production in the children. Allergy 2001; 56: 39. EAACI Berlin 2001.

20. Janefjord CK, Jenmalm MC. Phytohemagglutinin-induced interleukin-12 receptor β2 mRNA expression in atopic and non-atopic children. Allergy 2001; 56 suppl 68: 109. EAACI Berlin 2001.

21. Böttcher MF, Gustafson S, Voor T, Björkstén B, Jenmalm MC. Endotoxin levels in Estonian and Swedish house dust and atopy in infancy. CIA 2002 Bermuda.

22. Böttcher MF, Jenmalm MC, Björkstén B. Immune responses to birch in young children during their first seven years of life. Allergy 2002; 57: 43. EAACI Naples 2002.

23. Janefjord CK, Aniansson-Zdolsek H, Jenmalm MC. Reduced IL-12 receptor β2 up-regulation after IL-2 and IL-12 stimulation in atopic children. Allergy 2002; 57: 129. EAACI Naples 2002.

24.Janefjord CK, Jenmalm MC. CD2 induced calcium responses and IL-12Rβ2 mRNA expression in relation to atopy. J Allergy Clin Immunol 2003; 111: 2: S117. AAAAI Denver 2003.

25.Jenmalm MC, Rae J, Cherwinski H, Phillips JH, Curnutte JT, Sedgwick JD. Regulation of myeloid cell function through the CD200 receptor. 2003 Keystone Symposia, Taos.

26. Böttcher MF, Hmani M, Lindström A, Jenmalm MC, Mai X-M, Nilsson L, Aniansson Zdolsek H, Björkstén B, Söderquist P, Vaarala O. TLR4 polymorphism is associated with development of atopic asthma and reduced LPS induced IL-12(p70) and IL-10 responses. 2003 Keystone Symposia, Keystone.

27. Voor T, Julge K, Böttcher MF, Jenmalm MC, Björkstén B. Atopic sensitization and clinical allergy in Estonian and Swedish infants. Allergy Clin Immunol Int 2003; 15. WAO Vancouver 2003.

28. Jenmalm MC, Böttcher MF, Voor T, Björkstén B. Immune development in Estonian and Swedish children during the first two years of life. CIA Bornholm 2004.

29. Jenmalm MC, Böttcher MF, Voor T, Julge K, Holt PG, Björkstén. Cytokine responses to allergens during the first two years of life in Estonian and Swedish children. J Allergy Clin Immunol 2006; 117: S256. AAAAI Miami Beach 2006.

30. Jenmalm MC, Lindström A, Böttcher MF, Voor T, Julge K, Björkstén. Endotoxin-induced cytokines from antigen-presenting cells during the first two years of life in Estonian and Swedish children. CIA Malta 2006.

31. Janefjord CK, Böttcher MF, Björkstén B, Jenmalm MC: Development of Th1, Th2 and Treg associated immunity during the first two years of life in relation to allergic disease. CIA Malta 2006.

32. Janefjord CK, Grenegård M, Fälth-Magnusson K, Jenmalm MC, Böttcher MF: CD2-induced Treg and Th1-like immunity in atopic subjects. CIA Malta 2006.

33. Sandberg M, Jenmalm MC: Analysis of IgG subclass antibodies to food and inhalant allergens with Luminex methodology. xSAMPLES Amsterdam 2006.

34. Sandberg M, Frykman A, Jonsson Y, Ernerudh J, Berg G, Matthiesen L, Ekerfelt C, Jenmalm MC: Total and allergen specific IgE antibody levels during and after pregnancy in relation to allergic disease and cytokine responses to paternal antigens. J Allergy Clin Immunol 2007; 119: S211. AAAAI San Diego 2007.

35. Abrahamsson TR, Jakobsson T, Böttcher MF, Fredrikson M, Jenmalm MC, Björkstén B, Oldaeus G: Probiotics in prevention of IgE-associated eczema: a double blind randomised placebo-controlled trial. J Allergy Clin Immunol 2007; 119: S237. AAAAI San Diego 2007.

36. Sandberg M, Frykman A, Ernerudh J, Berg G, Matthiesen L, Nilsson L, Ekerfelt C, Jenmalm MC: Cord blood levels of cytokines and development of allergic disease. EAACI Gothenburg 2007.

37. Tomičić S, Voor T, Julge K, Jenmalm MC, Björkstén B, Böttcher MF: Mucosal immune responses in Estonian and Swedish mothers and children in relation to microbial exposure and atopic development. EAACI Gothenburg 2007.

38. Sandberg M, Frykman A, Jonsson Y, Ernerudh J, Berg G, Matthiesen L, Ekerfelt C, Nilsson L, Jenmalm MC: Total IgE Antibody levels dring and after pregnancy in relation to cord blood (CB) macrophage derived chemokine (MDC, CCL22) levels and allergic disease. ECRI Berlin 2007.

39. Sjögren YM, Jenmalm MC, Björkstén B, Sverremark-Ekström E: Bacterial DNA in infant faecal samples, as assessed by Real-time PCR, in relation to allergy development in children up to five years of age. WAO Bangkok 2007.

40.Sjögren YM, Björkstén B, Böttcher MF, Sverremark-Ekström E, Jenmalm MC: Endotoxin levels in house dust and early infant gut microbiota. CIA Curaçao 2008.

41. Tomičić S, Voor T, Jenmalm MC, Björkstén B, Böttcher MF: Development of mucosal immune responses in Estonian and Swedish children in relation to microbial exposure and development of allergic disease. MIVAC Gothenburg 2008.

42. Jenmalm MC, Böttcher MF, Voor T, Julge K, Björkstén B: Foxp3 expression during the first two years of life in Estonian and Swedish children. WIRM Davos 2008.

43. Sandberg M, Ernerudh J, Berg G, Matthiesen L, Ekerfelt C, Nilsson L, Jenmalm MC: Systemic Th1- and Th2- associated chemokines during and after pregnancy in relation to maternal allergic disease. EAACI Barcelona 2008.

44. Abrahamsson TR, Vaarala O, Björkstén B, Jenmalm MC: IgE-associated allergic disease during infancy is associated with low levels of C-reactive protein at one year of age. EAACI Barcelona 2008.

45. Edström M, Dahle C, Jenmalm MC, Mellergård J, Mjösberg J, Press R, Vrethem M, Ernerudh J: Th1/Th2/Th17 and Treg associated transcription factors in multiple sclerosis. J Neuroimmunol 2008; 203: 131-2. 9th International Congress of NeuroImmunology Fort Worth 2008.

46. Sjögren YM, Tomičić S, Lundberg A, Böttcher MF, Björkstén B, Sverremark-Ekström E, Jenmalm MC: Early infant gut microbiota and salivary IgA production in children. 2009 Keystone Symposia, Taos.

47. Abrahamsson TR, Sandberg M, Forsberg A, Björkstén B, Jenmalm MC: A Th1/Th2-associated chemokine imbalance preceding allergic disease is influenced by birth size, breastfeeding, daycare and probiotics. EAACI Warsaw 2009.

48. Mjösberg J, Berg G, Ernerudh J, Jenmalm MC, Matthiesen L: Enrichment of Foxp3+ Tregs and reduction of TH17 cells in human early pregnancy decidua indicate immunosuppressive T cell dominance. 29th Annual ASRI Meeting Orlando 2009.

49. Mjösberg J, Svensson J, Johansson E, Hellström L, Casas R, Jenmalm MC, Boij R, Matthiesen L, Berg G, Ernerudh J: Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17ß-estradiol. 29th Annual ASRI Meeting Orlando 2009.

50. Sandberg M, Ernerudh J, Berg G, Matthiesen L, Ekerfelt C, Nilsson L, Jenmalm MC: High cord blood CCL17 and CCL22 levels precede the development of allergic disease and sensitisation during the first 6 years of life. WIRM Davos 2010.

51. Mjösberg J, Berg G, Jenmalm MC, Ernerudh J: Foxp3+ regulatory T cells, Th1, Th2 and Th17 cells in human early pregnancy decidua. WIRM Davos 2010.

52. Johansson E, Berg G, Ernerudh J, Jenmalm MC, Mjösberg J: Production of Th1, Th2, and Th17-related factors and subunits of the inhibitory cytokine IL-35 in regulatory T cell suppression in pregnancy. WIRM Davos 2010.

53. Svensson J, Berg G, Jenmalm MC, Ernerudh J: CD14+ decidual macrophages from early human pregnancy: expression of markers associated with alternatively activated macrophages and requirements for their polarization. WIRM Davos 2010.

54. Abrahamsson TR, Sandberg M, Forsberg A, Björkstén B, Jenmalm MC: A Th1/Th2-associated chemokine imbalance preceding allergic disease is influenced by birth size, breastfeeding, daycare and probiotics. CIA Ischia 2010.

55. Mehta RB, Mirrasekhian E, Johansson E, Mjösberg J, Ernerudh J, Jenmalm MC: Characterization of human trophoblasts as immunomodulators. ESF-JSPS Frontier Science Conference for Young Researchers. Cutting Edge Immunology and its Clinical Application. Hulshort 2011.

56. Forsberg A, Abrahamsson TR, Jenmalm MC: Probiotic supplementation with Lactobacillus reuteri is associated with a reduced allergen responsiveness at two years of age. WIRM Davos 2011. Best poster prize.

57. Mehta RB, Huynh A, Janson PC, Winqvist O, Jenmalm MC, Ernerudh J: Epigenetic regulation of CD4+ T lymphocytes during pregnancy. WIRM Davos 2011.

58. Abelius M, Ernerudh J, Berg G, Matthiesen L, Nilsson L, Jenmalm MC: Immunological interactions between mother and child, a characterisation of Th1- and Th2-like chemokines during pregnancy, postpartum and childhood. ESRI Copenhagen 2011.

59. Mehta RB, Mirrasekhian E, Svensson J, Freland S, Berg G, Sharma S, Jenmalm MC, Ernerudh J: Immunomodulatory effects of trophoblast cells: Production of IL-35 and modulation of macrophage polarization. ESRI Copenhagen 2011.

60. Svensson J, Jenmalm MC, Matussek A, Geffers R, Berg G, Ernerudh J: Gene expression and protein secretion pattern in decidual macrophages and different M1 and M2 macrophage populations with focus on M-CSF and IL-10 as polarizing factors. ESRI Copenhagen 2011.

61. Persson M, Ekerfelt C, Jablonowska B, Jonsson Y, Ernerudh J, Jenmalm MC, Berg G: Immunologic status in patients undergoing in vitro fertilization. ESRI Copenhagen 2011.

62. Forsberg A, Straka E, Johansson E, Mehta R, Berg G, Jenmalm MC, Mjösberg J, Ernerudh J: Plasticity and flexibility of T cells in human pregnancy. ESRI Copenhagen 2011.

63. Forsberg A, Abrahamsson TR, Jenmalm MC: Maternal and infant Lactobacillus reuteri supplementation is associated with a reduced allergen responsiveness at two years of age. Wallenberg Symposium in Reproductive Immunology Linköping 2011.

64. Mehta RB, Huynh A, Janson PC, Winqvist O, Jenmalm MC, Ernerudh J: T helper lineage methylation profiling of CD4+ T cells in pregnancy. Wallenberg Symposium in Reproductive Immunology Linköping 2011.

Förkortningar:

AAAAI American Academy of Allergy Asthma and Immunology
ASRI American Society of Reproductive Immunology
CIA Collegium Internationale Allergologicum
EAACI European Academy of Allergy and Clinical Immunology
ESF European Science Foundation
ESPACI European Society of Paediatric Allergy and Clinical Immunology
IAACI International Academy of Allergy and Clinical Immunology
MIVAC Mucosal Immunology and Vaccine Center
WAO World Allergy Organization
WIRM World Immune Regulation Meeting

2011 Professor i Experimentell Allergologi, Linköpings Universitet (LiU)

2006 Docent i Experimentell Pediatrisk Immunologi, LiU

1995-1999 Forskarutbildning i Pediatrisk Allergologi, LiU
Lab. hos Prof Bengt Björkstén, MD, PhD, Avd f Pediatrik, Linköping &
Prof Patrick Holt, MD, PhD, Inst f Child Health Res, Perth, WA

1990-1994 Fil mag Biokemi, LiU

Arbetsgivare Anställningsgrad BörjadeSlutade
Statligt - Universitet - Linköpings universitet - Hälsouniversitetet
 100% 2004

1999- -Kursansvarig Scientific Methodology på Mastersnivå ht 2009 och forskarutbildningskurserna Immunological techniques ht 2009 samt Advanced Immunology vt 2011, Mentor för Masters-studenter Biomedical Sciences ht 2009. Terminsansvarig, biträdande terminsansvarig, basgruppshandledare, scenariokonstruktör, laborationsansvarig, tentator och föreläsare Medicinsk Biologi, LiU samt medlem i Sektorsgruppen f Immunologi. Scenariokonstruktör och föreläsare vid Läkarlinjen T2, T4, T10 och T11, vice ordf i temagruppen Immun, hud och infektion, fristående kurser LiU samt läkemedelskonsulentkurser, Allergicentrum i Linköping. Medverkat vid planering av kursen Immunobiologi och immunologiska tekniker för Teknisk Biologi.

1997- -Handledare vid åtta 20 p examensarb Biologi, fem 10 p och två 20 p arb vid Biomed Forskarskolan, ett 10 p arb Medicinsk Biologi samt fyra 10 p och ett 5 p fördjupningsarb Läkarlinjen

Utbildning

2006 Docent i Experimentell Pediatrisk Immunologi, Linköpings Universitet (LiU)

1995-1999 Forskarutbildning i Pediatrisk Allergologi, LiU
Lab. hos Prof Bengt Björkstén, MD, PhD, Avd f Pediatrik, Linköping &
Prof Patrick Holt, MD, PhD, Inst f Child Health Res, Perth, WA

1990-1994 Fil mag Biokemi, LiU

Forskningserfarenhet

2009 --Docent Avd f Inflammationsmedicin (lektorat 2011), Inst f Klinisk o Experimentell Medicin (IKE), LiU Huvudhandledare tre doktorander, bitr handledare två doktorander

2007 - 2009 Docent Avd f Pediatrik, IKE, LiU
Huvudhandledare två doktorander, bitr handledare tre doktorander

2004 -2007 Doktorsanställning ‘Utveckling av immunsvar i relation till atopi och miljö’
Avd f Pediatrik, Inst f Molekylär o Klinisk Medicin (IMK), LiU
Huvudhandledare två doktorander (en disputerad 06/06)

2002 - 2004 Post-doktorsanställning ‘Reglering av myeloida celler via CD200-receptorn’
Dept of Discovery Research, DNAX Research Inc, Palo Alto, CA, USA

1999 - 2002 Forskarassistenttjänst ‘Utveckling av immunsvar i relation till atopi och miljö’
Avd f Pediatrik, IMK, LiU (Föräldraledig oktober 2000-november 2001)
Huvudhandledare två doktorander, Bitr handledare en doktorand (disp 11/02)

1995-1999 Avhandling ‘Development of IgG subclass antibodies to allergens in early childhood’
Avd f Pediatrik, LiU, varav 8 mån hos Prof Patrick Holt 1997-98

1994-1995 Forskningsprojekt ‘Regulation of platelet function via the low affinity IgE receptor’
⋅hos Dr Magnus Grenegård, PhD, Avd f Farmakologi, LiU

Vetenskapliga priser och utmärkelser



Medlem av Collegium Internationale Allergologicum -06
Fernströmpriset, Linköpings Universitet 2007 (till ung, särskilt lovande och mycket framgångsrik forskare)

Vetenskapliga uppdrag (1996 - -)

Inbjuden föredragshållare vid 17 internationella kongresser och 8 nationella möten, presenterat poster vid 8 internationella kongresser och muntlig presentation vid 12 internationella kongresser

Refereeuppdrag för följande internationella tidskrifter: Allergy, Arch Oral Biol, Clin Exp Allergy, Int Arch Allergy Appl Immunol, Pediatr Allergy Immunol, World Allergy Org J. Editorial board för Allergol Immunopathol.

Inbjuden expert av European Commission vid Workshop 08-11-17 rörande "Combating Allergy and Asthma in Europe: Issues and Perspectives" i Bryssel.

Sakkunnig i Bryssel vid EU FP7 HEALTH.2010.2.4.5-1: Investigation of the mechanisms of
initiation of allergic response, genetic predisposition, biomarkers and identification of
targets for therapy. Funding scheme: Collaborative Large-scale Project.

Bedömare Karolinska Institute Inflammation and Immunology (KiiM) forskarnätverk.

Ledde LiU-Junior Faculty med 25%-ig tjänst från rektorskansliet Jan 2008 - April 2009.

Styrelseledamot Universitetsholding i Linköping AB fr o m 2010.

Opponent 060922 vid Anna-Karin Larssons disputation, Wenner-Gren-Institutet, Stockholm samt 110610 vid Sara Johanssons disputation, Chalmers.
Betygsnämnd vid följande disputationer; 070510 Akter Hossain, LiU, 070511 Charlotte Admyre, Karolinska Institutet, 080314 Johanna Dernfalk, SLU, 080328 Sofi Johansson, Göteborgs Univ, 091002 Tiiu Saarne, KI, 100213 Hanna Grindebacke, Göteborgs Univ, 110902 Karlhans Che, LiU, 111014 Mats Persborn, LiU (lic) & 111216 Veronica Tjomsland, LiU.

Publikationer

53 publ. originalarbeten (9 som första och 16 som sista författare) i internationella referee-granskade tidskrifter, 7 översiktsartiklar och 64 konferenssammanfattningar (19 som första, 23 som sista förf.).

Erhållna forskningsanslag (som huvudsökande, 1996- -)

Vetenskapsrådet / Hjärt-Lungfonden / Astma- och Allergifonden / Vårdalstiftelsen / Ekhagastiftelsen / Olle Engkvists Stiftelse/ FORSS / Cancer- & Allergifonden / Förstamajblommans Riksförbund / Knut och Alice Wallenbergs Stiftelse för Kvinnliga Nydisputerade / Lions Fo.fond / MFR Metodikstudier f Doktorander / Schelins Stiftelse / Stiftelsen Barnmedicinsk Fo / Stiftelsen Samariten / Sv Allergifo Stiftelse / Sv Sällskapet f Med Fo / Linköpings Universitet / Östergötlands läns landsting / 3MPharma och Rhône Poulenc Rorer

Erhållna resestipendier (1997- - )

Sv Föreningen f Allergologi / Hjärt-Lungfonden / European Academy of Allergy and Clinical Allergology / Wenner-Gren Stiftelserna / Novartis Stiftelse f Med-Biol Fo Knut o Alice Wallenbergs Jubileumsfond och Anna Cederbergs Stiftelse för Medicinsk Forskning

Forskarstuderande

Huvudhandledare för:

Camilla Janefjord, PhD, disputerade 060602
Thomas Abrahamsson, MD, PhD, disputerade 091001
Martina Sandberg, halvtidskontroll 090225
Marie Persson, halvtidskontroll 110616
Anna Forsberg, registrerad 110201

Bitr handledare för:

Helena Abrahamsson-Zdolsek, disputerade 021115
Måns Edström, halvtidskontroll 100906 (Prof Jan Ernerudh huvudhandledare)
Judit Svensson, halvtidskontroll 101213 (Prof Jan Ernerudh huvudhandledare)

Pedagogisk erfarenhet

1999- -Kursansvarig Scientific Methodology på Mastersnivå ht 2009 och forskarutbildningskurserna Immunological techniques ht 2009 och Advanced Immunology vt 2011, Mentor för Masters-studenter Biomedical Sciences ht 2009. Terminsansvarig, biträdande terminsansvarig, basgruppshandledare, scenariokonstruktör, laborationsansvarig, tentator och föreläsare Medicinsk Biologi, LiU samt medlem i Sektorsgruppen f Immunologi. Scenariokonstruktör och föreläsare vid Läkarlinjen T2, T4, T10 och T11, vice ordf i temagruppen Immun, hud och infektion, fristående kurser LiU samt läkemedelskonsulentkurser, Allergicentrum i Linköping. Medverkat vid planering av kursen Immunobiologi och immunologiska tekniker för Teknisk Biologi.

1997- -Handledare vid åtta 20 p examensarb Biologi, fem 10 p och två 20 p arb vid Biomed Forskarskolan, ett 10 p arb Medicinsk Biologi samt fyra 10 p och ett 5 p fördjupningsarb Läkarlinjen

Laboratorietekniker

Cellodling, ELISA, Luminex, CBA, realtids-PCR, isolering av celler från blod och vävnad, MACS, flödescytometri, EILA (epigenetic immune lineage analysis)

Föräldraledighet

Oktober 2000 – oktober 2001

Informationen är tillförlitlig | uppdaterad: 2011-12-14 av Maria Jenmalm |
Personkort för Maria Jenmalm, från FoU i Sverige
http://www.fou.nu/is/sverige/user/html/5476