personkort Hans-Jürg Monstein, Klinisk Mikrobiologi, Molekylärbiologiskt Laboratorium, DC

Basuppgifter

namn:
Hans-Jürg Monstein
arbetsplats:
Klinisk Mikrobiologi, Molekylärbiologiskt Laboratorium, DC
yrkestitel:
Molekylärbiolog
e-post

Arbete

arbetsplats:
Klinisk Mikrobiologi, Molekylärbiologiskt Laboratorium, DC
telefon:
arbetsgivarkategori:
Universitet/Högskola
adress:
Universitetssjukhuset
postadress:
58185 Linköping
land:

CV

Article - Peer reviewed scientific (22)

  1. Monstein H J, Philipson L.
    Nucleic Acids Res. 1981:9(17):4239-50.
  2. Monstein H J, Quednau M, Samuelsson A, Ahrné S, Isaksson B, Jonasson J.
    Microbiology (Reading, Engl.) 1998:144:1171-9.
    Web of Science® citations 39
  3. Tiveljung A, Söderholm J D, Olaison G, Jonasson J, Monstein H J.
    J Med Microbiol. 1999:48(3):263-8.
    Web of Science® citations 38
  4. Monstein H J, Ohlsson B, Axelson J.
    Scand J Gastroenterol. 2001:36(7):738-43.
    Web of Science® citations 11
  5. Scand J Gastroenterol. 2002:37(1):112-9.
    Web of Science® citations 31
  6. Hällgren Anita, Saeedi Baharak, Nilsson Maud, Monstein Hans-Jürg, Isaksson Barbro, Hanberger Håkan, Nilsson Lennart E.
    J Antimicrob Chemother. 2003:52(2):162-7.
    Web of Science® citations 16
  7. Samuelsson A, Jonasson J, Monstein H-J, Berg S, Isaksson B.
    J Hosp Infect. 2003:54(3):188-95.
    Web of Science® citations 3
  8. Sun Yi-Qian, Petersson Frederik, Monstein Hans-Jürg, Söderholm Johan D, Rehfeld Jens F, Borch Kurt.
    Scand J Gastroenterol. 2005:40(10):1157-67.
    Web of Science® citations 6
  9. European surgical research Europäische chirurgische Forschung Recherches chirurgicales européennes 2006:38(5):464-8.
    Web of Science® citations 3
  10. Monstein H-J, Ostholm-Balkhed A, Nilsson M V, Nilsson M, Dornbusch K, Nilsson L E.
    APMIS 2007:115(12):1400-8.
    Web of Science® citations 32
  11. European surgical research Europäische chirurgische Forschung Recherches chirurgicales européennes 2008:40(1):34-40.
    Web of Science® citations 12
information Nedan visas publikationer tillfälligt inlagda som text innan de konverteras till publikationsdatabasen.

Vetenskapliga publikationer

LIST OF PUBLICATIONS

Articles and reviews (peer-reviewed)

1974
1.The host factor requirement of QB RNA replicase. Kamen, R.I., Monstein, H-J., and Weissamn, C. (1974) Biochimica et Biophysica Acta 336, 292-299.

2.The readthrough protein A1 is essential for the formation of viable QB particles. Hofstetter, H., Monstein, H-J., and Weissman, C. (1974) Biochimica et Biophysica Acta 374, 238-251.

1981
3.Adenovirus early gene products may control viral mRNA accumulation and translation in vivo. Persson, H., Monstein, H-J., Akusjärvi, G., and Philipson, L. (1981) Cell, 483-486.

4.The conformation of adenovirus VAI-RNA in solution. Monstein, H-J., and Philipson, L. (1981) Nucleic Acids Research 9, 4239-4250.

5. Human DNA sequences complementary to the small nuclear RNA U2. Westin, G., Nucleic Acids Research Monstein, H-J., Zabielski, J., Philipson, L., and Pettersson, U. (1981) 9, 6323-6338.

1982
6.A candidate gene for human U1 RNA. Monstein, H-J., Westin, G., Philipson, L., and Pettersson, U. (1982) The EMB Journal 1, 133-137.

7.Small nuclear RNAs are encoded in the nontranscribed region of ribosomal spacer DNA. Reichel, R., Monstein, H-J., Jansen, H-W., Philipson, L., and Benecke, B-J. (1982) Proc. Natl Acad. Sci. USA 79, 3106-3110.

8. Doctoral thesis: Small nuclear RNAs in eukaryotic cells - A structural and funcional analysis. Monstein, H-J. (1982) Acta universitatis Upsaliensis.

1983
9.Loci for human U1 RNA - Structural and evolutionary implications. Monstein, H-J., Hammarström, K., Westin, G., Zabielski., Philipson, L., and Pettersson, U. (1983) J. Mol. Biology, 167, 245-257.

1984
10.Clustered genes for human U2 RNA. Westin, G., Zabielski, J., Hammarström, K., Monstein, H-J., Bark, C., and Pettersson, U. (1984) Proc. Natl. Acad. Sci. USA 81, 3811-3815.

1986
11.A rapid and inexpensive method for preparing E. coli plasmid-DNA. Monstein, H-J. and Geijer, T. (1986) Biochem. Internat. 12, 889-896.

12.Proenkephalin A-like mRNA in human leukemia leukocytes and CNS-tissues. Monstein, H-J., Folkesson, R., and Terenius, L. (1986) Life Sciences 39, 2237-2241.

1988
13.Expression of the proenkephalin gene in human neuroblastoma cell lines. Folkesson, R., Monstein, H-J., Geijer, T., Pålman, S., Nilsson, K., and Terenius, L. (1988) Mol. Brain Research 3, 147-154.

14. A highly sensitive northern blot assay detects multiple proenkephalin A-like mRNAs in human caudate nucleus and pheochromocytoma. Monstein, H-J. and Geijer, T. (1988) Bioscience Reports, 8, 255-262.

1989
15.Modulation of proenkephalin A gene expression by cyclic AMP. Folkesson, R., Monstein, H-J., Geijer, T., and Terenius, L. (1989) Molecular Brain Research 5,211-217.

16.Consturction of a multipurpose E. coli vector. Recloning and expression of the human proenkephalin A cDNA in E. coli. Monstein, H-J. (1989) Meth. in Mol. and Cell. Biology, 1, 115-119.

1990
17.Procholecystokinin and proenkephalin A mRNA expression is modulated by cyclic AMP and noradrenaline. Monstein, H-J., Folkesson, R., and Geijer, T. (1990) J. of Molecular Endocrinology 4, 37-41.

18.Expression of the cholecystokinin gene in a human (small cell) lung carcionoma cell-line. Geijer, T., Folkesson, R., Rehfeld, J.F., and Monstein, H-J. (1990) FEBS Letters 270. 30-32.

19.Expression of a human proenkephalin A cDNA in E. coli. Monstein, H-J. (1990) Bioscience Reports 10, 461-467.

1991
20.The expression of peptide hormones in normal cells and tumor cells. Rehfeld, J. F., Bardram, L., Blanke, S., Cantor, P., Friis-Hansen, L., Hilsted, L., Johnsen, A. H., Monstein, H.-J., van Solinge, W., Ödum, L., Örskov, C. (1991) Acta Oncol. Scand. 30, 429-433

21.Phorbol 12-myristate-13-acetate (PMA) stimulates a differential expression of cholecystokinin (CCK) and c-fos mRNA in a human neuroblastoma cell line. Monstein, H-J. and Folkesson, R .(1991) FEBS Letters, 293, 145-148.

1992
22.Cloning and expression of two different genes from streptococcus dysgalactiae encoding fibronectin receptors. Lindgren, P.E., Speziale, P., McGavin, M., Monstein, H-J., Höök, M., Visai, L., Kostiainen, T., Bozzini, S., and Lindberg, M. (1992) J. of Biological Chemistry, 267, 1924-1931.

23.Expression but failing maturation of procholecystokinin in cerebellum. Rehfeld, J.F., Mogensen, N.W., Bardram, L., Hilsted, L., and Monstein, H-J. (1992) Brain Research, 576, 111-119.

24.Modulation of cholecystokinin (CCK) gene-expression in a human neuroblastoma cell line: Effects of serum on enhanced CCK and c-fos mRNA expression. Monstein, H-J., Pedersen, K., and Haahr, P.M. (1992) Neuropeptides, 23, 107-113.

25.Blotto-MF, an inexpensive and reliable hybridization solution in Northern blot analysis using complementary RNA-probes. Monstein, H-J., Geijer, T., and Bakalkin, G.Y. (1992) BioTechniques, 13, 842-844.

26.A rapid and high yield procedure to prepare plasmid DNA using a modified Qiagen column system. Monstein, H-J. (1992) Methodes in Molecular and Cell Biology 3, 204-205.

1993
27. Peptide hormone processing in tumors: Biogenetic and diagnostic implications. Rehfeld, J. F., Bardram, L., Blanke, S., Bundgaard, J. R., Friis-Hansen, L., Hilsted, L., Johnson, A. H., Kofod, M., Lüttichau H. R., Monstein, H.-J., Nielsen, F. C., Paloheimo, L. I., Pedersen, K., Pildal, J., Ramlau, J., van Solinge, W., Ödum, L. (1993) Tumor Biology, 14, 174-183

28.Identification of an AP-1 transcription factor binding site within the human cholecystokinin (CCK) promoter. Monstein, H-J. (1993) NeuroReport 4, 195-197.

29.Modulated cholecystokinin (CCK) mRNA expression is dependent on de novo protein synthesis. Monstein, H-J. (1993) NeuroReport 4, 1167-1170.

30.cDNA deuduced procionin: structure and expression in protochordates resemble that of procholecystokinin in mammals. Monstein, H-J., Thorup. J.U., Folkesson, R., Johnsen, A., and Rehfeld, J.F. (1993) FEBS Letters 331, 60-64.

1994
31. The biology and physiology of the ECL cell. Håkanson, R., Chen, D., Andersson, K., Monstein, H.-J., Zhao, C. M., Ryberg, B., Sundler, F., Mattson, H. (1994) Yale J. of Biology and Medicine, 67, 123-135

32.Acute responses of rat stomach ECL cells to Gastrin: Secretory activation and adaption. Chen, D, Monstein, H-J., Nylander, A-G., Zhao, C.M., Sundler, F., and Håkansson, R.(1994) Gastroenterology, 107, 18-27.

1995
33.Genomic structure of the gene encoding Cionin-a Cholecystokinin/Gastrin like peptide. Monstein, H.-J. (1995). Neuro Report 6,253-256.

34.Vitamin D3 effects on basal and cAMP mondulated expression of CCK and somatostatin genes in a rat medullary thyroid carcinoma cell line (CA-77). *dum, L.Bundgaard, J.R., Monstein, H.-J., (1995) Neuropeptides, 29, 45-52.

35.RNA extraction from Gastrointestinal Tract and Pancreas by a modified Chomczynski and Sacchi Method. Monstein, H.-J., Nylander. A.G., Chen, D. (1995) Bio Techinques 19, 340-343.

36.Broad-range PCR amplification and DNA sequence analysis reveals variable motifs in 16S rRNA genes of Mobiluncus Species. Tivenljung, A., Backström, J., Forsum,U., Monstein, H.-J. (1995), APMIS, 103, 755-763.

1996
37.Classification of the genus Mobiluncus based on comperative partial 16S rRNA gene analysis, Tivenljung, A., Forsum, U., Monstein, H.-J. (1996) Int. J. Syst. Bacterol. 46, 332-336.

38.Detection an identification of bacteria using in-house broad range 16S rDNA amplification and genus-specific DNA hybridization probes, located within variable regions of 16S rRNA genes. Monstein, H.-J., Kihlström E., Tiveljung, A. (1996) APMIS, 104, 451-458.

39.Rat stomach ECL cells are not stimmulatedt by pylorus ligation. Zhao, C.M., Chen, D., Monstein, H.-J., Ding, X.-Q., Sundler F., Håkanson, R. (1996) Scand. J. Gastroenterology 31, 31-27.

40. CCK-A and CCK-B/gastrin receptor mRNA expression in the gastrointestinal tract and pancreas of rat and man. A polymerase chain reaction study. Monstein, H.-J., Nylander, A.-G., Salehi, A., Chen, D., Lundquist, I, Håkanson, R. (1996) Scand. J. Gastroenterology, 31, 383-390

41. Depletion of ECL-cell Histamine elevates Histidine Decarboxylase and Chromogranin
A mRNA levels in rat stomach by a Gastrin independent mechanism. Andersson, K. Lindström, E., Chen, D., Monstein, H.-J., Boketoft, Å., Håkanson, R. (1996) Scand. J. Gatroenterology 31, 959-965.

42.Release of preprotachykinin-A mRNA from rabbit iris upon noxious/stimulation. Wang, Z.Y., Monstein, H.-J., Håkanson, R. (1996) Eur. J. Pharmacology 297, 157-163.

1997
43.Electroconvulsive treatment evokes release of preprotachykinin-A mRNA into the cerebrospinal fluid and ocular agueous humor of rabbits. Wang, Z.Y., Monstein, H.-J., Waldeck, K., Grundemar, L., Håkanson, R. (1997). Neuroscience Letters,226, 151-154.

44.Increased expression of m RNA for the CCK-A Receptor in Pancreas and the CCK-B receptor in Oxytic Mucosa after Portacaval Shunting in Rats. Nylander, A.-G., von Friesen, C., Monstein, H.-J., Yamada, H., Chen. D., Boketoft, A., Håkanson, R., (1997) Pharmacol. Toxicology, 80, 147-151.

45.Effects of fasting on the expression of Gastrin, CCK and somatostatin Genes and of various house-keeping genes in the Pancreas and uppper digestive tract of Rats. Yamada, H., Chen. D., Monstein, H.-J., Håkanson, R. (1997) Biochem. Biophys. Res. Commun., 231, 835-838.

46.Widespread expression of Gastin binding protein mRNA. Monstein, H.-J., Nylander, A.G., Håkanson R. (1997) Europ. J. Biochemistry 246, 502-507

47.A-Fluoromethylhistidine elevates histidine decarboxylase mRNA and chromogranin A mRNA levels in rat oxyntic mucosa. Lindström, E., Anderson, K., Chen, D., Monstein, H.-J., Boketoft, A., Håkanson, R. (1997) Inflamm. Research 46, Suppl. 1, s107-108

48.The genus Mobiluncus – 16S rRNA gene analysis versus phenotypic characterization. Forsum, U., Monstein, H.-J., Tiveljung, A. (1997) Int. J. SDS and AIDS, 8, Suppl. 1, 7-8.

1998
49.Division of the genus Enterococcus into species groups using PCR-based molecular typing methods. Monstein H.-J., Quednau, M., Samuelsson, A., Ahrne, S., Isaksson, B., Jonasson, J. (1998) Microbiology, 144, 1171-1179.

50. Identification of Helicobacter in human gastric biopsies by PCR based on 16S rDNA sequences: a matter of little significance for the prediction of H. Pylori associated gastritis? Tiveljung, A., Borch, K., Mårdh, S., Petterson, F., Monstein, H.-J. (1998) J. Med. Microbiology 47, 695-7.

51.Non-random fragmentation of ribosomal RNA in Helicobacter pylori during conversion to the coccoid form. Monstein, H.-J., Tiveljung, A., Jonasson, J. (1998) FEMS Immunology and Med. Microbiology 22, 217-224.

52.Cloning and characterisation of 5’-end alternatively spliced human cholecystokinin-B receptor mRNAs. Monstein, H.-J., Nilsson, I., Ellnebo-Svedlund, K., Svensson, S. (1998) Recepors and Channels 6, 165-177.

1999
53.Presence of eubacteria in biopsies from Crohn’s tissues as determined by 16S rRNA gene based PCR. Tiveljung, A., Söderholm, J., Olaison, G., Jonasson, J., Monstein, H.-J. (1999) J. Med. Microbiology 46, 263-268.

2000
54.Detection of vancomycin-resistance genes combined with typing of Enterococci by
means of multiplex PCR-amplification and multiple primer DNA sequencing. Monstein H.-J., Johansson, Y., Jonasson, J. (2000). APMIS 108, 67-73.

55.Profiling of bacterial flora in gastric biopsies from patients with Helicobacter- associated gastritis and histologically normal control individuals by temperature gradient gel electrophoresis and 16S rDNA sequence analysis. Monstein, H-J., Tiveljung, A., Kraft, Ch., Borch, K., and Jonasson, J. (2000). J Med Microbiology, 49, 817-822.

56.Detection and identification of fungi in blood using broad-range 28S rDNA PCR amplification and species specific hybridisation. Evertsson, U., Monstein, H-J., Johansson, A. (2000), APMIS, 108, 385-392.

2001
57.Identification of enterococcal isolates by temporal temperatur gel electrophoresis and partial sequence analysis of PCR amplified 16S rDNA variable V6 regions. Monstein, H-J., Ahrné, S., Molin, G. Nikpour Badr S., Jonasson, J.(2001). APMIS, 109, 209-216

58.Arbitrarily primed PCR and sequencing of 16S rDNA for epidemiological typing and species identification of Burkholderia cepacia isolates from swedish patientds with cystic fibrosis reveal genetic heterogeneity. Karpati, F., giedraitis, V., Thore, M., Lindman, R., Monstein, H-J., Hjelte, L., Jonasson, J. (2001) APMIS,109, 389-400.

59.Rapid molecular identification and subtyping of Helicobacter pylori by pyrosequencing of the 16S rDNA variable V1 and V3 regions. Monstein, H-J., Nikpour-Badr, S., Jonasson, J. (2001).FEMS Microbiology Letters, 199, 103-107.

60.Probing 23S ribosomal RNA cleavage sites in coccoid Helicobacter pylori. Monstein H-J., Charlotta D. de la Cour, Jonasson, J. (2001). Helicobacter, 6, 100-109

61.Differential virulence-gene mRNA expression in coccoid forms of Helicobacter pylori. Monstein, H-J., Jonasson, J. (2001). Biochem Biophys Res Commun, 285, 530-536

62.Differential expression of Gastrin, Cholecystokinin-A, and Cholecystokinin-B receptor mRNA in human pancreatic cancer cell lines. Monstein, H-J., Ohlsson, B., Axelson, J.(2001) Scand J Gastroenterology, 36, 738-743

2002

63.Pharmacological analysis of CCK2 receptor ligands using COS-7 and SK-N-MC cells, expressing the human CCK2 receptor. Nilsson, I.B.M., Monstein, H-J., Lindström, E., Håkanson, R., Svensson, S.P.S.(2002). Regulatory Pepides, 103, 29-37.

64.Identification of Helicobacter pylori DNA in human cholesterol gallstones. Monstein, H-J., Johansson, Y., Zdolsek J., J., Svanvik, J. (2002). Scand J Gastroenterology, 37, 112-119.

65.Classification, identification and subtyping of bacteria based on pyrosequencing and signature matching of 16S rDNA fragments. Jonasson, J., Olofsson, M., Monstein, H-J. (2002). APMIS 110, 263- 272

66.Molecular typing of Helicobacter pylori by virulence-gene based multiplex PCR and RT-PCR analysis. Monstein, H-J., Ellnebo-Svedlund, K. (2002). Helicobacter 7, 287-296.

2003

67.Profiling and identification of eubacteria in the stomach of Mongolian gerbils with and without Helicobacter pylori infection. Sun, Y-Q* , Monstein, H-J*., Nilsson, LE., Petersson , F., Borch, K. (2003). Helicobacter 8, 149-157.
* The first two authors contributed equally to the study.

68.Identification of mixed bacterial DNA contamination in broad-range PCR-amplification of 16S rDNA V1 and V3 variable regions by pyrosequencing of cloned amplicons. (2003). Grahn, N., Olofsson, M., Ellnebo-Svedlund, K., Monstein, H-J., Jonasson, FEMS Microbiology Letters 219, 87-91.

69.Genetic relatedness among Enterococcus faecalis with transposon carried high-level gentamicin-resistant enterococci in Swedish intensive care units (2003). Hällgren, A., Saeedi, B., Monstein, H-J., Nilsson, M., Isaksson, B., Hanberger, H., Nilsson, L. J Antimicrob Chemother, 52, 162-167.

70.Molecular typing of the bacterial flora in sputum of cystic fibrosis patients (2003). Kolak, M., Karpati, F., Monstein, H-J., Jonasson, J. Int J Med Microbiology, 293, 309-317.

71.Clustering of enterococcal infection in a general intensive care unit (2003). Samuelsson, A., Jonasson, J., Monstein, H-J., Berg, S., Isalsson, B. J Hospital Infection, 54, 188-195.

72.Molecular cloning of an unusual bi-cistronic cholecystokinin receptor mRNA expressed in chicken brain. A structural and functional expression study. (2003). Nilsson, IBM., Svensson, SPS., Monstein, H-J. Regulatory Peptides, 114, 37-43.

2004
73.Molecular cloning of a putative Ciona intestinalis cionin receptor, a new member of the CCK/gastrin family (2004). Nilsson, IBM., Svensson, SPS., Monstein, H-J. GENE, 323, 79-88.

74.Oxytocin and Oxytocin receptor mRNA expression in the human gastrointestinal tract: a polymerase chain reaction study (2004). Monstein, H-J., Truedsson, M., Grahn, N., Ohlsson, B. Regul Peptides, 119, 39-44.

75.Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas. (2004). Fransén, K., Klintenäs, M., Österström, A., Dimberg, J., Monstein, H-J., Söderkvist, P. Carcinogenesis, 25, 527-533.

76.K-ras and B-raf mutations are not associated with gastrin and CCK2 receptor mRNA expression in human colon and rectal cancer tissues (2004). Monstein, H-J., Fransén, K., Dimberg, J., Söderkvist, P. Europ J Clin Investigation, 34, 100-106.

77.Molecular cloning and characterisation of two Helicobacter pylori genes coding for plasminogen-binding proteins. (2004). Jönsson, K., Guo, B., Monstein, H-J., Mekalanos, JJ., Kronvall G. Proc Natl Acad Sci USA, 101, 1852-1857.

2005

78.Effect of human milk on type 1 and P fimbrial mRNA expression in intestinal Escherichia coli strains (2005). Nowrouzian, F., Monstein, H-J., Wold A. E., Adlerberth, I . Lett Appl Microbiology, 40, 74-80.

79.Long-term H. pylori-induced gastritis in Mongolian gerbils: Morpho-functional development and pro-inflamatory cytokine expression (2005). Sun, Yi-Q., Petersson, F., Monstein, H-J., Söderholm, J. D., Rehfeld, J. F., Borch, K. Scand J Gastroenterology, 40, 1157-1167.

80.Molecular identificatioin of Helicobacter-DNA in human colorectal adenocarcinomas by 16S rDNA multi-step PCR amplification and pyrosequencing analysis (2005). Grahn, N., Hamani-Aifa, M., Fransén, K., Söderkvist, P., Monstein, H-J. J Med Microbiology, 54, 1031-1035.

81.Multiple displacement amplification of isolated DNA from human cholesterol gallstones: Molecular identification of Helicobacter-DNA by means of 16S rDNA-based pyrosequencing analysis (2005). Nilsson, I., Shabo, I., Svanvik, J. Monstein, H-J., Helicobacter,10, 592-600.

82.Multiple displacement amplification of DNA from human colon and rectum biopsies: Bacterial profiling and identification of Helicobacter pylori-DNA by means of 16S rDNA-based TTGE and pyrosequencing analysis (2005). Monstein, H-J., Olsson, C., Nilsson, I., Grahn, N., Benoni, C., Ahrné, S. J Microbiol Methods, 63, 239-247.
2006

2006

83.Progastrin-releasing peptide and gastrin-releasing peptide receptor mRNA expression imn non-tumor tissues of the human gastrointestinal tract (2006). Monstein, H-J., Grahn, N., Truedsson, M., Ohlsson, B. World J Gastroenterology, 12, 2576-252578.

84.Proenkephalin-A mRNA is widely expressed in tissues of the human gastrointestinal tract. Monstein, H-J., Grahn, N., Ohlsson, B (2006). European Surgical Research, 38, 464-468.

2007

85.Multiple strand displacement amplification of DNA isolated from archival plasma/serum: identification of cytokine polymorphism by pyrosequencing analysis (2007). Sun, Y-Q., Monstein, H-J., Ryberg, A., Borch, K. Clinica Chimica Acta, 377,108-113.

86.Multiplex PCR amplification assay for the detection of blaSHV, blaTEM and blaCTX-M genes in Enterobacteriaceae (2007). Monstein, H-J., Östholm-Balkhed, Å., Nilsson, M. V., Nilsson, M., Dornbusch, K., Nilsson, L. E. APMIS 115: 1400-1408.

2008

88.Vasopressin receptor mRNA expression in the human gastrointestinal tract (2008). Monstein, H-J., Truedsson, M., Ryberg, A., Ohlsson, B (2008). Eur Surg Res 40:34-40.

89. Concurrent genotyping of Helicobacter-specific virulence genes and human cytokine SNP-sites using whole genom amplified DNAderived from minute amounts of biopsy specimens (2008). Ryberg,A., Sun, Y-Q., Borch, K., Monstein, H-J. BMC Microbiol 8:175 Highly accessed.

2009

90. Molecular identification of blaCTX-M and blaOXY/K1 beta-lactamase grenes in Enterobacteriaceae by sequencing of universal M13- sequence-tagged PCR amplicons. Monstein, H-J., Tärmberg, M., Nilsson, L.E. (2009). BMC Infect Dis 9:7.

91. Molecular identification of blaSHV, blaLEN and blaOKP beta-lactamase genes in Klebsiella pneumoniae by bi-directional sequencing of universal SP6- and T7-sequence-tagged blaSHV-PCR amplicons. Tärnberg, M., Nilsson, L.E., Monstein, H-J. (2009). Mol Cell Probes 23:195-200.

92. Molecular detection of aggregation substance, enterococcal surface protein, and cytolysin genes and in vitro adhesion to urinary catheters of Enterococcus faecalis and E. faecium of clinical origin. Hällgren, A., claesson, C., Saeedi, B., Monstein, H-J., Hanberger, H., Nilsson, L.E. (2009). Int J Med Microbiol 299:323-332.

93. Application of PCR amplicon sequencing using a single sequence-tagged primer-pair in PCR amplification to assess variations in Helicobacter pylori cagA 3'-region encoding Caga EPIYA tyrosin phosphorylation motifs. Monstein, H-J., Karlsson, A., Ryberg, A., Borch, K. (2009) submitted to BMC Microbiology

Övriga publikationer

Proceedings and Abstracts

1.A translation control of adenovirus early gene expression. Persson, H., Monstein, H-J. and Philipson, L. (1980) at the EMBO-workshop on Molecular Biology of Adenoviruses, Peebles, Scotland.

2.The control of adenovirus early gene expression. Persson, H., Monstein, H-J., and Philipson, L. (1980) in Expression of Eukaryotic viral and Cellular Genes, ed. by Pettersson, R. et al., Academic Press, New York.

3.The control of adenovirus early gene expression. Persson, H. Monstein, H-J., and Philipson, L. (1980) in Genes and Tumor Genes p. 1-1o 9th Workshop Conference Hoechst. ed. by Winnacker, E.L., and Shoene, H.H. Raven Press, New York.

4.Analysis of genes for small nuclear RNA-molecules. Westin, G., Monstein, H-J., Zabielski, J., Philipson, L., and Pettersson, U. (1981) at the Scandinavian E.M. Society, Huddingen Hospital, Sweden.

5.Genes and pseudogenes for human snRNAs. Westin, G., Monstein, H-J. Zabielski, J., Hammarström, K, Philipson, L., and Pettersson, U. (1982) at the Cold Spring Harbor-meeting on "RNA-Processing".

6.Loci for human U1 RNA - A strucural analyses. Monstein, H-J., Hammarström, K., Westin, G., Zabielski, J., Philipson, L. and Pettersson, U. (1983) "Low molecular weight RNA-species of Eukaryotic Cells" in Hoppe-Seyler's Zeitschrift für Phgysiologische Chemie. Bd 364, July 1983.

7.Loci for human U1, U2, and U4. Hammarströ, K., Monstein, H-J., Westin, G., Bark, C., Zabielski, J., Philipson, L., and Pettersson, U. (1983) at the Cold Spring Harbor-meeting on "RNA-Processing"

8.New approaches for endorphin studies in psychiatry. Nyberg, F. Monstein, H-J., and Terenius, L. (1985) in Neuropeptides in Psychiatric Research, ed. by Widerlöv, E., and Knorring, L., Nordic Journal of Psychiatry, Suppl. No. 11, vol. 39.

9.Post-translational attenuation of Neuropeptide Expression. Rehfeld, J.F., Blanke, S., Hilsted, L., Johnsen, A., Monstein, H-J., and *dum, L. (1989) in Neuropeptides and their Receptor, Alfred Benzon Sjymposium 29, Copenhagen, Denmark.

10.Generation of recombinant DNA probes to be used as diagnostic tools. Monstein, H-J. (1989) Danish Society for Clinical Chemistry, University Hospital Copenhagen, September 1989.

11.CCK/Gastrin and proenkephalin A gene expression in the human neuroblastoma cell line SK-N-MC. Monstein, H-J., Rehfeld, J.F., and Folkesson, R., (1990) "3rd Sandbjerg-Symposium on Neuropeptides" in Acta Neurologica Scand. vol. 81, April 1990.

12.Cell-specific expression and processing of procholecystokinin and progastrin in "Gastrointestinal Endocrinology" (1990) (Eds by J.C. Thompsen, Academic Press) Rehfeld, J.F., Bardram, L., Blande, S., Cantor, P., Folkesson, R., Hilsted, L., Johnsen, A.H., Monstein, H-J., van Solinge, W.W., *dum, L.

13.Basic methods in Clinical Molecualr Bilogy - a compilation. Monstein, H-J. and Pedersen, K. (1991) Dept. of Clinical Biochemistry, State University Hospital, Copenhagen

14. Expression and regulation of the human cholecystokinin gene. Pedersen, K., Monstein, H-J., and Rehfeld, J.F. (1992) Keystone Symposium on Molecular and Cellular Biology, in J. of Cellular Biochem, Suppl. 16B, H533.

15.Modulation of CCK-gene expression: a possible role of Fos/Jun involvement. Monstein, H-J.. (1992) 9th Int. Symp. Gastroint. Hormones, Leuven, Belgium in Regulatory Peptides, 40, 212.

16.Expression of the gastrin and CCK genes in the developing rat hypothalamus. Monstein, H-J., Pedersen, K., Mikkelsen, J.D., and Rehfeld, J.F. (1992) 9th. Int. Sypm. Gastroint. Hormones, Leuven, Belgium in Regulatory Peptides, 40, 212.

17. Rat stomach ECL-cells. acute responses to Gastrin. Chen, D., Zhao, C-M., Nylander, A.G., Monstein, H-J., Sundler, F. and Håkanson, R. (1993) Pharmacol. and Toxicol. 72, Suppl. II, 84.

18. Gastrin does not stimulate the growth of the rat pancreas. Chen, D., Monstein, H-J., Nylander, A-G., and Håkanson, R. (1993) Digestion, 54, P26G, # 17 (XXV-th meeting: European Pancreatic Club, Paris.

19.Gastrin does not stimulate the growth of the rat pancreas. Chen, D.,Monstein, H-J., Nylander, A-G., and Håkanson, R. Internat. conference on GI-Hormones, Peking, (1993) Chinese Med. Sci.J.,8, Suppl. A005

21.cDNA deduced procionin: structure and expression pattern in protochordates resembles that of procholecystokinin in mammals (1994). Ann. N.Y. Acad. Science, 713. 324-327, Thorup, J.U., Monstein, H-J., Johnsen, A.H., Renfeld, J. F. In: Cholecystokinin, eds: Reeves, J.R., Esselein, V., Solomon, T.E., Go, U.L. N.Y. Acad, Sci., Publication Dept (New York)

21.A time table of rat stomach ECL cell responnses to Gastrin (1995) Chen. D.,
Zhao, C-M., Monstein, H-J., Nylander, A-G., Tielemans, Y., Sundler, F., Håkansson, R. in Gastrointestinal tract and Endocrine System, p. 178-185. Eds: Singer, M. V. Ziegler, R., Roler, G., Kluwer Acad. Publisher, London.

22.A time table for activation of ECL-cells in rat Stomach by Gastrin. Chen,D,.Håkansson,R., Monstein, H-J., Tielemans, Y., Sundler, F., Nylander, A-G., Zhao, C-M. (1994) GI-tract and endocrine system (Freiburg, Germany)

23.Tissue distribution of CCK-A CCK-B/Gastrin receptor mRNA. Monstein, H.-J., Nylander, A.-G., Salehi, A., Chen, D., Lundquist, I., Håkansson, R. (1995) European Neuropepide Club; 5th Annual Meeting, Lund University, Lund, Sweden. Pharmacol. and Toxicol. 76, Suppl. IV, 1995, A 61.

24.Classification of Genus Mobiluncus based on partial 16S rRNA Gene sequences. Tivenljung, A., Forsum, U. Monstein, H.-J., (1995) Svenska Läkarnas Riksstämman, Stockholm, Sek. Med. Mikrobiologi, Hygea 104; 259-260.

25.CCK-A and CCK-B/gastrin Receptor mRNAs in Gastrointestinal Tract and Pancreas of Rat and Humans. Monstein, H.-J., Nylander, A.-G., Salehi, A., Chen. D., Lundquist, I., Håkansson, R, (1995). Int J Pancreatology, 18, p. 286.

26.Bacterial Diagnosis using a broad range PCR amplification and genus specific hybridization approach: Evalution of intraspecies 16S rDNA sequence variation of Mobiluncus species. Tivenljung, A., Backström, J., Forsum, U., Monstein, H.-J. (1996) in: Report of the first scand. Society of vaginal vaginosis, Gothenburg, Feb. 1995; Acta Obstet. Gynecol. Scand., 75, 194-197.

27. Depletion of ECL-cell histamine elevates histidine decarboxylase and chromogranin A mRNA levels in rat oxyntic mucosa. Lindström, E., Andersson, K., Chen, D., Monstein, H.-J., Boketoft, A., Håkanson, R. (1996), 25th meeting May 22-25, 1996; Antwerp, Belgium; Europ. Histamine Res Society.

28.Detection and identification of C trachomatis using broad range PCR amplification and genus-specific 165 rDNA hydridzation. Kihlström, E., Tiveljung, A., Monstein, H.-J, (1996) 3d. European Chlamydia meeting, September 11-14, 1996. Vienna, Austria.

29.Cholecystokinin-A and Cholecystokinin-B/Gastrin Receptor mRNA Expression in Gastrointestinal Tract and Pancreas of the Rat an d Man. A PCR study. Nylander A.-G., Monstein H.-J., Salehi A., Chen, D., Lundquist I. and Håkansson R. (1996) Reg Pept. 64 nos.
1-3 p. 144.

30.Increased Expression of mRNA for the CCK-A Receptor in Pancreas and the CCK-B Receptor in Oxyntic Mucosa after Porta-caval Shunting in Rats. Nylander A.-G., Paz von Friesen C., Monstein H.-J i Yamada H., Chen D, Boketoft Å. and Håkansson R. (1996) Reg Pept. 64 nos. 1-3 p. 144.

31.Release of preprotachykinin-A mRNA from Rabbit iris upon C-fibre stimulation. Wang Z.-Y., Monstein H.-J., Håkansson R. (1996) Reg Pept. 64 nos. 1-3 p. 205.

32.Influence of Prandial State on the Gene Expression of Gastrin, Cholecystokinin, Somatostatin, Actin, GAPDH, 18S rRNA in Pancreas and Upper Digestive Tract of Rats. Yamada H., Nylander A.-G., Chen D., Kimura K. and Monstein H.-J.. (1996) Reg Pept. 64 nos. 1-3 p. 211

33.Detection of fungal DNA in blood speciemens using broad-range primers for the 28S rRNA gene. Evertsson, U., Monstein, H-J., Sören, L., Johansson, A. (1997) P 378, Int. Soc. Human Anim. Mycology, Parma (Italy), June 8-13

34.Detection of bacteria by 16S rRNA gene based amplification and genus specific hybridisation analysis in cholesterol gallstones. Monstein, H-J., Tiveljung, A., Zdolesk, J., Svanvik, J. (1998). AGA meeting, New-Orleans, May 1998. Gastroenterology, 114, part 2. G2173

35.Bakreriell flora i magbiopsier, studerad med 16S rDNA baserade tekniker och temporal temperatur gradient gel elektrofores (TTGE). Tiveljung, A., Jonasson, J., Monstein, H-J., et al. Riksförening för Mikrobiologi, Föreningen för Medicinsk Mikrobiologi, Vårmöte 2000, April 10-12, Malmö, Sweden.

36.Expression of the CCK-B receptor and gastrin mRNA in human pancreatic cancer cell lines. Monstein, H-J, Ohlsson, B., Rehfeld, J. F., Axelson, J. (2000). 32nd European Pancreatic Club. June 29 – juli 1 in Kiel, Germany

37.Identification of Helicobacter pylori DNA in the center of human cholesterol gallstones. Monstein, H-J., Jonsson, Y., Zdolsek, L., Svanvok, J (2001). The thirty-third Nordic meeting of Gastrornterology. Reykjavik, June 9-12. Scand J Gastroenterol. 2001, 34 suppl. 233:27.

38.Virulence-gene mRNA levels are related to non-random fragmentation of ribosomal RNA in coccoid Helicobacter. Monstein, H-J., Jonasson J. (2001). Int J Med Microbiology K-20. CHRO-2001. 11th International Workshop on Campylobacte, Helicobacter and related organisms. September 1-5, Freiburg, Germany.

39.Profiling and identification of eubacteria in the stomach of Mongolian gerbils with and without Helicobacter pylori infection. Sun Yi-Qian, Monstein H-J., Nilsson LE., Petersson F., Borch K (2002). 5th International workshop on pathogenesis and host response in Helicobacter infections. LO-Skolen, Helsingör, Demnmark, July 4 – 7.

40.Molecular cloning and characterisation of two Helicobacter pylori genes coding for plasminogen binding proteins. Guo, B, Jönsson, K., Monstein, H-J., Mekalanos, J.; Kronvall, G. (2003). Int J Med Microbiology O-50. CHRO-2003. 12th International Workshop on Campylobacte, Helicobacter and related organisms. September 6-10, Aarhus, Denmark.

41.Commentary to : Classification, identification and subtyping of bacteria based on pyrosequencing and signature matching of 16S rDNA fragments. Jonasson, J., Monstein, H-J (2007). The Swedish Sciciety for Medical Microbiology. Activities and scientific success during the first 100 years. APMIS 115:678-679.

Teaching and educational experiences

1978-1982: Lectures and practical teaching in microbiology at the undergraduate level at the Dept of Microbiology, Uppsala University.

Autumn 1983-86: Invited guest lecturer in the field of nucleic acid biochemistry/
molecular biology, at the Dept of Biochemistry, Uppsala University.

Autumn 1983-86: Lectures and seminars in cellular and molecular biology and supervision of graduate students at the Dept of Pharmacology, Uppsala University.
Superviser of cand.phil. Thomas Geijer in molecular biology. Publications, #11,14,17,18,24.

Spring 1986-88: Lectures in molecular biology and gene-technology at the Dept of Microbiology, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Molecular biology superviser of P.E.Lindgren (Disputation May 1992). Publication #21.

April 1984: Organizer of a graduate course in "Molecular Approaches to Endocrinology and Neurobiology".

June 1988-1992: Continuous supervision of graduate/undergraduate students and technical staff members in molecular biology/clinical molecular biology at the Dept of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark.

Supervisor of dr.pharm.vet. Ronnie Folkesson, who was a postdoc in my laboratory from september 1988 - may 1991. Publications #17,18,21,30.
Molecular biology supervisor of lic.stud. Karin Pedersen. Publication #24, and Laboratory manual: ”Basic Methods in Clinical Molecular Biology”.

Supervisor of stud.scient. Jan Ulrik Thorup, who received his cand.scient. degree in microbiology/molecular biology from the University of Copenhagen in October 1992. Thesis: ”Molecular cloning and characterization of the cDNA encoding the protochordean neuropeptide Cionin; A novel member of the mammalian CCK/GA family”, publication #30.

1993 - 1998: Dept of Pharmacology, University of Lund, Sweden: lectures, seminars in cellular and molecular biology

Molecular Biology supervisor at the Dept of Pharmacology, Lund University:
Duan Chen, (Disputation May, 1994) publication # 32.
Anna-Greta Nylander (Disputation March, 1996), publictions # 35, 40, 44, 46,
Zun Yi Wang (Disputation December, 1996) publications #42, 43.
Erik Lindström, publications #41, 47, (Disputation may 2000)
Charlotta D. De la Cour

Examination – board (Betygsnämnd)
Member of the examination-board (Betygsnämnd) for doctoral dissertations (Disputation) at the Faculty of Health Sciences Linköping (Microbiology, Cellular and Molecular Biology); Örebro University Hospital (Microbiology); Swedish University of Agricultural Sciences (Microbiology-SLU) Uppsala; Karolinska Institute, (Clinical Microbiology, Experimental Oncology) Stockhom.

Faculty opponent (Examinator)
Disputation Dr. Martin Storm, Dept of Clinical Microbiology, Uppsala University; March 24, 2006

Supervision of students (general)

Since1982 I have build up and initiated teaching and research activities in molecular biology at 5 different Institutes.
Supervision and teaching of undergraduate/graduate students in molecular biology has led to the following numbes of degrees at:

Dep of Pharmacology, University of Uppsala;
1 Ph.D, 2 B.Sc.

Dept of Microbiology, SLU, Uppsala;
1 Ph.D.

Dept of Clinical Biochemistry, Copenhagen;
1 Post doc, 1 M.Sc.

Dept of Pharmacology, Lund (supervisor in Molecular Biology)
4 Ph.D.

Faculty of Health Sciences, Linköping University, linköping,
3 Ph.D., 12 M.Sc., 5 BMA (B.Sc and M.Sc)

Technicians (BMA) which have enrolled practical education at the Molecular Biology Laboratory-LMC, Linköping (since 1993):

Erika Jacobsson (autumn 1997) 20p Examination work on: ”Identification of bacteria in gallstones with broad-range PCR, based on 16S rRNA gene sequences”

Shoreh Nikpour-Badr (autumn 1996) 20p Examination work on: ”Epidemiologisk karakterisering av kliniska Enterokock-isolate med molekylärbiologisk metodik” (Characterisation of enterococcal clinical isolates by means of molecular biology methods).

Shoreh Nikpour-Badr (spring 1999) Examination work as part of her MSc-degree in Biomedical Laboratory Technology Science, 61-80p
Literature review: ” Review on vancomycin resistant Enterococci (VRE) and identification of VRE by means of molecular biology techniques".
Practical ex-work: ”Evaluation of multiplex PCR amplification and multiple primer DNA-sequencing as tools for detectin of vanvomycin resistant Enterococci”.

Katarina Ellnebo-Svedlund (autumn 2001) 20p Examination work as part of her M.Sc. degree (Uppsala University) "Evaluation of molecular biology techniques used for thr detection and characterisation of Helicobacter pylori virulence genes"

In collaboration with Örebro University (BMA- program):

Anna Christa Zetterblom (spring 2000) 20p Examination work on: ”Utveckling av multiplex PCR-amplifiering för detektion av Helicobacter pylori baserat på 16S rRNA, ureA, vacA, cagA, sod, och hsp60 generna. (Evaluation of multiplex PCR amplification as a means to identify Helicobacter pylori).

Sofia Braag (spring 2002) 10p Examination work as part of her BMA-degree at Orebro University. ”Karakterisering av bakterieflora i kolorektala cancerbiopsier med temperatur gradient gel elektrofores (TGGE) och Pyrosekvensering” (Characteriation of a bacterial flora in human colon-cancer biopsy specimens by means of TTGE and Pyrosequencing).

Supervison of M.Sc-students in Linköping (since 1993):

Annika Tiveljung
M.Sc. 1994 ”Broad-range bacterial diagnosis using PCR amplification based on 16S rRNA genes: evaluation of intraspecies variation within the 16S rRNA gene of Mobiluncus species”.

Magnus Samuelsson
M.Sc. 1994 ”PCR-cloning of CCK/Gastrin-like and receptor like cDNAs from two non-mammalian species”.

Yvonne Johansson
M.Sc. 1998 ”Development and application of multiplex PCR amplification and multiple primer DNA sequencing to detect vancomycin-resistance- genes in Enterococci”.

Charlotta de la Cour
M.Sc. 1999 ”Non-random fragmentation of 23S rRNA in
Helicobacter pylori during conversion to the coccoid form”.

Ulrika Zagai
M.Sc. 1999 ”Expression of UreA, Hsp60, and SOD messenger RNA i coccoid forms of Helicobacter pylori”.

Chamilly Gautam
M.Sc. 2000 ”Putative sod-promoter and enhancer DNA motifs in25 clinical isolates and the type strain CCUG 17874 of Helicobcter pylori ”

Niclas Grahn
M.Sc 2001 "Responsivness of Helicobacter pylori to human gastrin in liquid cultures"

Maria Klintenäs
M.Sc. 2002 ”Genetic engineering and expression of human recombinant Hepatocyte growth factor in E. coli.

Maria Klintenäs
Graduate School of Biomedical Research (Biomedicinsk Fo-skolan), Faculty of Health Sciences, University of Linköping, autumn 2002. “In vivo and in vitro expression of recombinant human hepatocyte growth factor”.

Anna Rydberg
M.Sc. 2004. “Locked Nucleic Acid (LNA) application as a capture probe in molecular diagnostics”.

Tove Bjerg
M.Sc 2004. “Helicobacter transcriptomics-a practical approach to RNA isolation”.

Pranuthi Muggalla
International M.Sc-program Umeå University, Department of Molecular Biology, 2005. “Helicobacter pylori transcriptomics-a practical approach to to prepare microarray grade RNA ”.

Pranuthi Muggalla
International M.Sc-program Umeå University, Department of Molecular Biology, 2006. “Helicobacter pylori transcriptomics-Evaluation of two different labelling techniques”.

Therése Klingstedt
M.Sc. 2006. “Whole genome amplification of DNA using multiple displacement amplification and a GenomePlex kit: Molecular identification of Helicobacter pylori virulence genes”

Sebastian Hedlund
Graduate School of Biomedical Research (Biomedicinsk Fo-skolan, report No 338), Faculty of Health Sciences, University of Linköping, autumn 2006.

Graduate students (Linköping)

Annika Tiveljung
PhD (2000). Dissertation No 622. “Identification and characterisation of bacteria based on 16S rDNA techniques with special reference to Helicobacter pylori in the gastro-intestinal tract.”

Isabelle Nilsson
PhD (2003). Dissertation No. 791. “The cholecystokinin receptor family. Molecular cloning and pharmacological characterization”

Yi-Qian Sun (Responsible supervisor in Molecular Biology)
PhD (2004). Dissertation No. 876. “Experimental Helicobacter pylori infection in an animal model”

Academics
Invited peer-reviewer for:

Acta Endocrinologica Scandinavica
Acta Physiologica Scandinavica
Alcohol
APMIS
Bio Techniques
BMC-Gastroenterology
Clinical Microbiology and Infection
European Journal of Biochemistry
European journal of Clinical Investigation
Europen Journal of Clinical Microbiology & Infectious Diseases
European Journal of Epidemiology
The Lancet
FEMS Microbiology Letters
Journal of Neuroscience Methods
Journal of Microbiological Methods
Regululatory Peptides

Editorial Board Member:
Journal of Microbiological Methods
Research & Reviews in BioSciences

Resursperson

Handledare

målgrupp och kostnad:
BMA, Biologer, Läkare, Teknologer
inriktning/beskrivning:
enligt CV:n
Informationen är tillförlitlig | uppdaterad: 2010-10-11 av Hans-Jürg Monstein |

Personkort för Hans-Jürg Monstein, från FoU i Sverige
http://www.fou.nu/is/sverige/user/html/4500