personkort David Ley, Barn- och Ungdomssjukhuset i Lund, Neonatalavdelningen

Basuppgifter

namn:
David Ley
arbetsplats:
Barn- och Ungdomssjukhuset i Lund, Neonatalavdelningen
yrkestitel:
Professor, Överläkare
e-post

Arbete

arbetsplats:
Barn- och Ungdomssjukhuset i Lund, Neonatalavdelningen
telefon:
046-178068
arbetsgivarkategori:
Specialiserad vård
adress:
Getingevägen 85
postadress:
211 85 Lund
land:
Sverige

CV

Article - Peer reviewed scientific (44)

  1. Doppler velocimetry in cerebral vessels of small for gestational age infants.
    Ley D, Marsál K.
    Early Hum Dev. 1992:31(2):171-80.
    [Links: PMID: 1292924][Source: PubMed®]
    Web of Science® citations 14
  2. Intrauterine blood flow and postnatal neurological development in growth-retarded fetuses.
    Marsál K, Ley D.
    Biol Neonate 1992:62(4):258-64.
    [Links: PMID: 1420624][Source: PubMed®]
    Web of Science® citations 15
  3. Agenesis of the ductus venosus and its correlation to hydrops fetalis and the fetal hepatic circulation: case reports and review of the literature.
    Sivén M, Ley D, Hägerstrand I, Svenningsen N.
    Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association 1995:15(1):39-50.
    [Links: PMID: 8736596][Source: PubMed®]
    Web of Science® citations 22
  4. Abnormal fetal aortic velocity waveform and minor neurological dysfunction at 7 years of age.
    Ley D, Laurin J, Bjerre I, Marsal K.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 1996:8(3):152-9.
    [Links: PMID: 8915083 | DOI länk][Source: PubMed®]
    Web of Science® citations 55
  5. Abnormal fetal aortic velocity waveform and intellectual function at 7 years of age.
    Ley D, Tideman E, Laurin J, Bjerre I, Marsal K.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 1996:8(3):160-5.
    [Links: PMID: 8915084 | DOI länk][Source: PubMed®]
    Web of Science® citations 48
  6. Aortic vessel wall characteristics and blood pressure in children with intrauterine growth retardation and abnormal foetal aortic blood flow.
    Ley D, Stale H, Marsal K.
    Acta Paediatr. 1997:86(3):299-305.
    [Links: PMID: 9099321][Source: PubMed®]
    Web of Science® citations 19
  7. Respiratory distress syndrome in infants with impaired intrauterine growth.
    Ley D, Wide-Swensson D, Lindroth M, Svenningsen N, Marsal K.
    Acta Paediatr. 1997:86(10):1090-6.
    [Links: PMID: 9350891][Source: PubMed®]
    Web of Science® citations 31
  8. Effectiveness of casein hydrolysate feedings in infants with colic.
    Jakobsson I, Lothe L, Ley D, Borschel M W.
    Acta Paediatr. 2000:89(1):18-21.
    [Links: PMID: 10677051][Source: PubMed®]
    Web of Science® citations 19
  9. Abnormal fetal aortic velocity waveform and postnatal growth.
    Ley D, Laurin J, Marsal K.
    Acta Paediatr. 2000:89(11):1330-5.
    [Links: PMID: 11106045][Source: PubMed®]
    Web of Science® citations 1
  10. Longitudinal follow-up of children born preterm: somatic and mental health, self-esteem and quality of life at age 19.
    Tideman E, Ley D, Bjerre I, Forslund M.
    Early Hum Dev. 2001:61(2):97-110.
    [Links: PMID: 11223272][Source: PubMed®]
    Web of Science® citations 32
  11. Reduced postnatal cerebral glucose metabolism measured by PET after asphyxia in near term fetal lambs.
    Thorngren-Jerneck K, Ley D, Hellström-Westas L, Hernandez-Andrade E, Lingman G, Ohlsson T, Oskarsson G, Pesonen E, Sandell A, Strand S E, Werner O, Marsal K.
    J Neurosci Res. 2001:66(5):844-50.
    [Links: PMID: 11746410][Source: PubMed®]
    Web of Science® citations 18
  12. Tolerance to early human milk feeding is not compromised by indomethacin in preterm infants with persistent ductus arteriosus.
    Bellander M, Ley D, Polberger S, Hellström-Westas L.
    Acta Paediatr. 2003:92(9):1074-8.
    [Links: PMID: 14599073][Source: PubMed®]
    Web of Science® citations 9
  13. Different responses of myocardial and cerebral blood flow to cord occlusion in exteriorized fetal sheep.
    Ley David, Oskarsson Gylfi, Bellander Mikael, Hernandez-Andrade Edgar, Lingman Göran, Marsal Karel, Olsson Tomas, Pesonen Erkki, Thorngren-Jerneck Kristina, Werner Olof, Hellström-Westas Lena.
    Pediatr Res. 2004:55(4):568-75.
    [Links: PMID: 14739362 | DOI länk][Source: PubMed®]
    Web of Science® citations 7
  14. Abnormal retinal vascular morphology in young adults following intrauterine growth restriction.
    Hellström Ann, Dahlgren Jovanna, Marsál Karel, Ley David.
    Pediatrics 2004:113(2):e77-80.
    [Links: PMID: 14754975][Source: PubMed®]
  15. Validation of fractional moving blood volume measurement with power Doppler ultrasound in an experimental sheep model.
    Hernandez-Andrade E, Jansson T, Ley D, Bellander M, Persson M, Lingman G, Marsál K.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2004:23(4):363-8.
    [Links: PMID: 15065186 | DOI länk][Source: PubMed®]
    Web of Science® citations 20
  16. Abnormal retinal optic nerve morphology in young adults after intrauterine growth restriction.
    Ley David, Marsal Karel, Dahlgren Jovanna, Hellstrom Ann.
    Pediatr Res. 2004:56(1):139-43.
    [Links: PMID: 15128920 | DOI länk][Source: PubMed®]
    Web of Science® citations 14
  17. Visual function in young adults following intrauterine growth retardation.
    Martin Lene, Ley David, Marsal Karel, Hellström Ann.
    Journal of pediatric ophthalmology and strabismus 2004:41(4):212-8.
    [Links: PMID: 15305531][Source: PubMed®]
    Web of Science® citations 14
  18. Impaired vascular growth in late adolescence after intrauterine growth restriction.
    Brodszki J, Länne T, Marsál K, Ley D.
    Circulation 2005:111(20):2623-8.
    [Links: PMID: 15883208 | DOI länk][Source: PubMed®]
    Web of Science® citations 29
  19. VWF-cleaving protease (ADAMTS13) in premature infants.
    Hellström-Westas Lena, Ley David, Berg Ann-Cathrine, Kristoffersson Ann-Charlotte, Holmberg Lars.
    Acta Paediatr. 2005:94(2):205-10.
    [Links: PMID: 15981755][Source: PubMed®]
    Web of Science® citations 6
  20. Perinatal adaptive response of the adrenal and carotid blood flow in sheep fetuses subjected to total cord occlusion.
    Hernandez-Andrade Edgar, Hellström-Westas Lena, Thorngren-Jerneck Kristina, Jansson Tomas, Liuba Karina, Lingman Göran, Marsál Karel, Oskarsson Gylfi, Werner Olof, Ley David.
    J Matern Fetal Neonatal Med. 2005:17(2):101-9.
    [Links: PMID: 16076616 | DOI länk][Source: PubMed®]
    Web of Science® citations 2
  21. Circulating interferon-gamma and white matter brain damage in preterm infants.
    Hansen-Pupp Ingrid, Harling Solveig, Berg Ann-Cathrine, Cilio Corrado, Hellström-Westas Lena, Ley David.
    Pediatr Res. 2005:58(5):946-52.
    [Links: PMID: 16183810 | DOI länk][Source: PubMed®]
    Web of Science® citations 22
  22. Umbilical cord levels of interleukin-1 receptor antagonist and neonatal outcome.
    Elsmén Emma, Ley David, Cilio Corrado M, Hansen-Pupp Ingrid, Hellstrom-Westas Lena.
    Biol Neonate 2006:89(4):220-6.
    [Links: PMID: 16301842 | DOI länk][Source: PubMed®]
    Web of Science® citations 4
  23. Increased fetal blood pressure response to maternal norepinephrine after pharmacological inhibition of norepinephrine uptake in pregnant sheep.
    Hansson S R, Bottalico B, Amer-Wahlin I, Marsál K, Ley D.
    Acta Paediatr. 2007:96(5):650-4.
    [Links: PMID: 17381469 | DOI länk][Source: PubMed®]
    Web of Science® citations 1
  24. Inflammation at birth and the insulin-like growth factor system in very preterm infants.
    Hansen-Pupp I, Hellström-Westas L, Cilio C M, Andersson S, Fellman V, Ley D.
    Acta Paediatr. 2007:96(6):830-6.
    [Links: PMID: 17465986 | DOI länk][Source: PubMed®]
    Web of Science® citations 16
  25. Cerebral inflammatory response after fetal asphyxia and hyperoxic resuscitation in newborn sheep.
    Markus Tina, Hansson Stefan, Amer-Wåhlin Isis, Hellström-Westas Lena, Saugstad Ola Didrik, Ley David.
    Pediatr Res. 2007:62(1):71-7.
    [Links: PMID: 17519806 | DOI länk][Source: PubMed®]
    Web of Science® citations 25
  26. Cognitive function in young adults following intrauterine growth restriction with abnormal fetal aortic blood flow.
    Tideman E, Marsál K, Ley D.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2007:29(6):614-8.
    [Links: PMID: 17523158 | DOI länk][Source: PubMed®]
    Web of Science® citations 18
  27. Inflammation at birth is associated with subnormal development in very preterm infants.
    Hansen-Pupp Ingrid, Hallin Anne-Li, Hellström-Westas Lena, Cilio Corrado, Berg Ann-Cathrine, Stjernqvist Karin, Fellman Vineta, Ley David.
    Pediatr Res. 2008:64(2):183-8.
    [Links: PMID: 18391842 | DOI länk][Source: PubMed®]
    Web of Science® citations 20
  28. Early amplitude-integrated EEG correlates with cord TNF-alpha and brain injury in very preterm infants.
    Wikström Sverre, Ley David, Hansen-Pupp Ingrid, Rosén Ingmar, Hellström-Westas Lena.
    Acta Paediatr. 2008:97(7):915-9.
    [Links: PMID: 18462469 | DOI länk][Source: PubMed®]
    Web of Science® citations 14
  29. High brain tissue oxygen tension during ventilation with 100% oxygen after fetal asphyxia in newborn sheep.
    Perez-de-Sa Valeria, Cunha-Goncalves Doris, Nordh Anders, Hansson Stefan, Larsson Anders, Ley David, Fellman Vineta, Werner Olof.
    Pediatr Res. 2009:65(1):57-61.
    [Links: PMID: 18703995 | DOI länk][Source: PubMed®]
    Web of Science® citations 5
  30. Tumor necrosis factor receptor-1 is essential for LPS-induced sensitization and tolerance to oxygen-glucose deprivation in murine neonatal organotypic hippocampal slices.
    Markus Tina, Cronberg Tobias, Cilio Corrado, Pronk Cornelis, Wieloch Tadeusz, Ley David.
    J Cereb Blood Flow Metab. 2009:29(1):73-86.
    [Links: PMID: 18728678 | DOI länk][Source: PubMed®]
    Web of Science® citations 5
  31. Fresh-frozen plasma as a source of exogenous insulin-like growth factor-I in the extremely preterm infant.
    Hansen-Pupp Ingrid, Engström Eva, Niklasson Aimon, Berg Ann-Cathrine, Fellman Vineta, Löfqvist Chatarina, Hellström Ann, Ley David.
    J Clin Endocrinol Metab. 2009:94(2):477-82.
    [Links: PMID: 19001522 | DOI länk][Source: PubMed®]
    Web of Science® citations 5
  32. A pharmacokinetic and dosing study of intravenous insulin-like growth factor-I and IGF-binding protein-3 complex to preterm infants.
    Löfqvist Chatarina, Niklasson Aimon, Engström Eva, Friberg Lena E, Camacho-Hübner Cecilia, Ley David, Borg Jan, Smith Lois E H, Hellström Ann.
    Pediatr Res. 2009:65(5):574-9.
    [Links: PMID: 19190540 | DOI länk][Source: PubMed®]
    Web of Science® citations 10
  33. Validation of a new retinopathy of prematurity screening method monitoring longitudinal postnatal weight and insulinlike growth factor I.
    Löfqvist Chatarina, Hansen-Pupp Ingrid, Andersson Eva, Holm Kristina, Smith Lois E H, Ley David, Hellström Ann.
    Arch Ophthalmol. 2009:127(5):622-7.
    [Links: PMID: 19433710 | DOI länk][Source: PubMed®]
  34. The influence of age on the distribution of morphine and morphine-3-glucuronide across the blood-brain barrier in sheep.
    Bengtsson J, Ederoth P, Ley D, Hansson S, Amer-Wåhlin I, Hellström-Westas L, Marsál K, Nordström C-H, Hammarlund-Udenaes M.
    Br J Pharmacol. 2009
    [Links: PMID: 19438510 | DOI länk][Source: PubMed®]
    Web of Science® citations 3
  35. Circulatory effects of inhaled iloprost in the newborn preterm lamb.
    Noponen Tommi, Nordh Anders, Berg Ansgar, Ley David, Hansson Stefan R, Pesonen Erkki, Fellman Vineta.
    Pediatr Res. 2009:66(4):416-22.
    [Links: PMID: 19581832 | DOI länk][Source: PubMed®]
    Web of Science® citations 2
  36. Early intervention in management of very preterm growth-restricted fetuses: 2-year outcome of infants delivered on fetal indication before 30 gestational weeks.
    Brodszki J, Morsing E, Malcus P, Thuring A, Ley D, Marsál K.
    Ultrasound Obstet Gynecol 2009:34(3):288-96.
    [Links: PMID: 19705404 | DOI länk][Source: PubMed®]
    Web of Science® citations 11
  37. New insights into the development of retinopathy of prematurity - importance of early weight gain.
    Hellström A, Ley D, Hansen-Pupp I, Niklasson A, Smith L, Löfqvist C, Hård A-L.
    Acta Paediatr. 2009
    [Links: PMID: 19878131 | DOI länk][Source: PubMed®]
    Web of Science® citations 14
  38. Fetal cerebral energy metabolism and electrocardiogram during experimental umbilical cord occlusion and resuscitation.
    Amer-Wåhlin Isis, Nord Anders, Bottalico Barbara, Hansson Stefan R, Ley David, Marsál Karel, Ungerstedt Urban, Nordström Carl Henrik.
    J Matern Fetal Neonatal Med. 2010:23(2):158-66.
    [Links: PMID: 20074023 | DOI länk][Source: PubMed®]
    Web of Science® citations 1
  39. Continuous monitoring of fetal scalp temperature in labor: a new technology validated in a fetal lamb model.
    Lavesson Tony, Amer-Wåhlin Isis, Hansson Stefan, Ley David, Marsál Karel, Olofsson Per.
    Acta Obstet Gynecol Scand 2010:89(6):807-12.
    [Links: PMID: 20504083 | DOI länk][Source: PubMed®]
    Web of Science® citations 0
  40. Beta-Adrenoceptor activation depresses brain inflammation and is neuroprotective in lipopolysaccharide-induced sensitization to oxygen-glucose deprivation in organotypic hippocampal slices.
    Markus Tina, Hansson Stefan R, Cronberg Tobias, Cilio Corrado, Wieloch Tadeusz, Ley David.
    Journal of neuroinflammation 2010:7(1):94.
    [Links: PMID: 21172031 | DOI länk][Source: PubMed®]
    Web of Science® citations 1
  41. Influence of Insulin-Like Growth Factor-I and Nutrition during Phases of Postnatal Growth in Very Preterm Infants.
    Hansen-Pupp Ingrid, Löfqvist Chatarina, Polberger Staffan, Niklasson Aimon, Fellman Vineta, Hellström Ann, Ley David.
    Pediatric research 2011
    [Links: PMID: 21263374 | DOI länk][Source: PubMed®]
  42. Postnatal Decrease in Circulating Insulin-Like Growth Factor-I and Low Brain Volumes in Very Preterm Infants.
    Hansen-Pupp Ingrid, Hövel Holger, Hellström Ann, Hellström-Westas Lena, Löfqvist Chatarina, Larsson Elna-Marie, Lazeyras Francois, Fellman Vineta, Hüppi Petra S, Ley David.
    The Journal of clinical endocrinology and metabolism 2011
    [Links: PMID: 21289247 | DOI länk][Source: PubMed®]
  43. Cognitive function after intrauterine growth restriction and very preterm birth.
    Morsing Eva, Asard Malena, Ley David, Stjernqvist Karin, Marsál Karel.
    Pediatrics 2011:127(4):e874-82.
    [Links: PMID: 21382944 | DOI länk][Source: PubMed®]
  44. Carbon dioxide and glucose affect electrocortical background in extremely preterm infants.
    Wikström Sverre, Lundin Fredrik, Ley David, Pupp Ingrid Hansen, Fellman Vineta, Rosén Ingmar, Hellström-Westas Lena.
    Pediatrics 2011:127(4):e1028-34.
    [Links: PMID: 21444592 | DOI länk][Source: PubMed®]
    Web of Science® citations 1

Book Chapter (2)

  1. Postnatal development in intrauterine growth restriction with abnormal fetal blood flow.
    Ley David, Marsal Karel.
    Doppler in obstetrics and gynecology. New York: Springer; 2005,
    [Source: User]
  2. Cirkulation.
    David Ley, Norman Mikael.
    Neonatologi. Studentlitteratur; 2009,
    [Source: User]

Accepterade men ännu ej publicerade publikationer

Markus T, Ley D, Hansson S, Wieloch T. Beta1-adrenoceptor activation is protective by down-regulating inflammation and apoptosis and up-regulating antioxidant defense. Journal of neuroinflammation.

Manuskript ännu ej accepterade för publikation

Sveinsdottir S, Cinthio M, Ley D. Use of high-frequency ultrasound in the evaluation of cerebral intraventricular hemorrhage in the preterm rabbit pup.

Sveinsdottir S, Ohlsson MG, Ruescher K, Åkerström B, Ley D. Scavenging of free hemoglobin down-regulates toll-like receptor 4 and down-stream mediators of inflammation after intraventricular hemorrhage in preterm rabbit pups.

Hansen-Pupp I, Hövel H, Löfkvist C, Fellman V, Hellström A, Ley D. Effects of postnatal change in IGF-I and nutritional intake on developmental outcome at 2 years of age in very preterm infants.

Harling S, Hansen-Pupp I, Dumitrescu A, Ley D, Pesonen E. Increased levels of Interleukin-8 are correlated to reduced systemic blood pressure but not with increased left to right ductal shunting in preterm infants.

Löfqvist C, Hellgren G, Niklasson A, Hansen-Pupp I, Engström E, Smith L, Hård A-L, Ley D, Hellström A. Early serum insulin-like growth factors and BPD: possible implications for lung angiogenesis.

Läkarexamen, Umeå Universitet, 1985
Legitimerad läkare, 1987
Specialist i Pediatrik, 1992
Specialist i Neonatologi, 1994
Disputation (PhD), 1997
Docent, 2004
Formell professorskompetens, Med fak, Lunds Universitet 2009
Utsedd professor, Avd f Pediatrik, Med Fak, Lunds Universitet, 2011
Arbetsgivare Anställningsgrad BörjadeSlutade
Landsting - Region Skåne - Specialiserad vård - Universitetssjukhuset MAS Show info
Onkologiska kliniken

 100% 1985 1986
Landsting - Region Skåne - Specialiserad vård - Sjukhuset i Hässleholm Show info
AT-tjänst

 100% 1986 1987
Landsting - Region Skåne - Specialiserad vård - Universitetssjukhuset MAS
 100% 1987 1992
Landsting - Region Skåne - Specialiserad vård - Universitetssjukhuset i Lund Show info
Neonatalavdelningen

 100% 1992

Forskningshandledning
Huvudhandledare för 4 doktorander:
Ingrid Hansen-Pupp, disputerat maj 2008
Tina Markus, disputerat maj 2009
Snjolaug Sveinsdottir, registrerad doktorand 2009
Kristbjörg Sveinsdottir, doktorand 2010
Bihandledare för:
Anna Kahn

Handlett 6 studenter i examensarbete
Examinator för 12 studenter (examensarbete)

Opponent vid 3 avhandlingar
Oulu 2005, Köpenhamn 2009, Göteborg 2011

Ledamot i 12 betygsnämnder

Övrig undervisning
Amanuens i grundutbildning för medicine kandidater (pediatrik kursen)
1991, 1996
Kursledare för ST- kurs i perinatalmedicin, 2000, 2001, 2002Ledamot i forskningsetisk kommitte (Lunds universitet) 2008-
Vald medlem i Eurpean Neonatal Brain Club 2000-
Ledamot i vetenskaplig nämnd, Lilla Barnets fond, 2009-
Medlem i forskningsstrategisk grupp, Med fak, Lunds Universitet, 2009-10.
Informationen är tillförlitlig | uppdaterad: 2012-02-13 av David Ley |
Personkort för David Ley, från FoU i Sverige
http://www.fou.nu/is/sverige/user/html/38451