personkort Caroline Wass, Center for Addiction and Menthal Health, Schizophrenia and Addiction Programs, Toronto, Canada

Basuppgifter

namn:
Caroline Wass
arbetsplats:
Center for Addiction and Menthal Health, Schizophrenia and Addiction Programs, Toronto, Canada
yrkestitel:
Postdoctoral Fellow
e-post

Arbete

arbetsplats:
Center for Addiction and Menthal Health, Schizophrenia and Addiction Programs, Toronto, Canada
telefon:
001-416-333-2760
arbetsgivarkategori:
Specialiserad vård
adress:
CAMH, 250 College Street
postadress:
 TORONTO, ON
land:
Canada

CV

Article - Peer reviewed scientific (14)

  1. The effects of phencyclidine on latent inhibition in taste aversion conditioning: differential effects of preexposure and conditioning.
    Pålsson Erik, Klamer Daniel, Wass Caroline, Archer Trevor, Engel Jörgen A, Svensson Lennart.
    Behav Brain Res. 2005:157(1):139-46.
    [Links: PMID: 15617780 | DOI länk][Source: PubMed®]
    Web of Science® citations 21
  2. Antagonism of the nitric oxide synthase inhibitor, L-NAME, of the effects of phencyclidine on latent inhibition in taste aversion conditioning.
    Klamer Daniel, Pålsson Erik, Wass Caroline, Archer Trevor, Engel Jörgen A, Svensson Lennart.
    Behav Brain Res. 2005:161(1):60-8.
    [Links: PMID: 15904710 | DOI länk][Source: PubMed®]
    Web of Science® citations 15
  3. Effects of phencyclidine on spatial learning and memory: nitric oxide-dependent mechanisms.
    Wass Caroline, Archer Trevor, Pålsson Erik, Fejgin Kim, Klamer Daniel, Engel Jörgen A, Svensson Lennart.
    Behav Brain Res. 2006:171(1):147-53.
    [Links: PMID: 16677724 | DOI länk][Source: PubMed®]
    Web of Science® citations 21
  4. Phencyclidine affects memory in a nitric oxide-dependent manner: working and reference memory.
    Wass Caroline, Archer Trevor, Pålsson Erik, Fejgin Kim, Alexandersson Asa, Klamer Daniel, Engel Jörgen A, Svensson Lennart.
    Behav Brain Res. 2006:174(1):49-55.
    [Links: PMID: 16935357 | DOI länk][Source: PubMed®]
    Web of Science® citations 23
  5. The amino acid L-lysine blocks the disruptive effect of phencyclidine on prepulse inhibition in mice.
    Pålsson Erik, Fejgin Kim, Wass Caroline, Engel Jörgen A, Svensson Lennart, Klamer Daniel.
    Psychopharmacology (Berl.) 2007:192(1):9-15.
    [Links: PMID: 17235609 | DOI länk][Source: PubMed®]
    Web of Science® citations 13
  6. The atypical antipsychotic, aripiprazole, blocks phencyclidine-induced disruption of prepulse inhibition in mice.
    Fejgin Kim, Safonov Sergej, Pålsson Erik, Wass Caroline, Engel Jörgen A, Svensson Lennart, Klamer Daniel.
    Psychopharmacology (Berl.) 2007:191(2):377-85.
    [Links: PMID: 17235612 | DOI länk][Source: PubMed®]
    Web of Science® citations 15
  7. Nitric oxide signaling in the medial prefrontal cortex is involved in the biochemical and behavioral effects of phencyclidine.
    Fejgin Kim, Pålsson Erik, Wass Caroline, Svensson Lennart, Klamer Daniel.
    Neuropsychopharmacology 2008:33(8):1874-83.
    [Links: PMID: 17895915 | DOI länk][Source: PubMed®]
    Web of Science® citations 21
  8. Nitric oxide synthase inhibition attenuates phencyclidine-induced disruption of cognitive flexibility.
    Wass Caroline, Svensson Lennart, Fejgin Kim, Pålsson Erik, Archer Trevor, Engel Jörgen A, Klamer Daniel.
    Pharmacol Biochem Behav. 2008:89(3):352-9.
    [Links: PMID: 18321564 | DOI länk][Source: PubMed®]
    Web of Science® citations 9
  9. Agmatine attenuates the disruptive effects of phencyclidine on prepulse inhibition.
    Pålsson Erik, Fejgin Kim, Wass Caroline, Klamer Daniel.
    Eur J Pharmacol. 2008:590(1):212-6.
    [Links: PMID: 18573247 | DOI länk][Source: PubMed®]
    Web of Science® citations 7
  10. Prefrontal GABA(B) receptor activation attenuates phencyclidine-induced impairments of prepulse inhibition: involvement of nitric oxide.
    Fejgin Kim, Pålsson Erik, Wass Caroline, Finnerty Niall, Lowry John, Klamer Daniel.
    Neuropsychopharmacology 2009:34(7):1673-84.
    [Links: PMID: 19145229 | DOI länk][Source: PubMed®]
    Web of Science® citations 10
  11. The importance of nitric oxide in social dysfunction.
    Wass Caroline, Klamer Daniel, Fejgin Kim, Pålsson Erik.
    Behav Brain Res. 2009:200(1):113-6.
    [Links: PMID: 19166879 | DOI länk][Source: PubMed®]
    Web of Science® citations 10
  12. Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function.
    Wallén-Mackenzie Asa, Nordenankar Karin, Fejgin Kim, Lagerström Malin C, Emilsson Lina, Fredriksson Robert, Wass Caroline, Andersson Daniel, Egecioglu Emil, Andersson My, Strandberg Joakim, Lindhe Orjan, Schiöth Helgi B, Chergui Karima, Hanse Eric, Långström Bengt, Fredriksson Anders, Svensson Lennart, Roman Erika, Kullander Klas.
    J Neurosci. 2009:29(7):2238-51.
    [Links: PMID: 19228977 | DOI länk][Source: PubMed®]
    Web of Science® citations 13
  13. Increased cortical nitric oxide release after phencyclidine administration.
    Pålsson Erik, Finnerty Niall, Fejgin Kim, Klamer Daniel, Wass Caroline, Svensson Lennart, Lowry John.
    Synapse 2009:63(12):1083-1088.
    [Links: PMID: 19642219 | DOI länk][Source: PubMed®]
    Web of Science® citations 7
  14. L-lysine as adjunctive treatment in patients with schizophrenia: a single-blinded, randomized, cross-over pilot study.
    Wass Caroline, Klamer Daniel, Katsarogiannis Evangelos, Pålsson Erik, Svensson Lennart, Fejgin Kim, Bogren Inga-Britt, Engel Jörgen A, Rembeck Birgitta.
    BMC Med 2011:9:40.
    [Links: PMID: 21501494 | DOI länk][Source: PubMed®]
    Web of Science® citations 1

Accepterade men ännu ej publicerade publikationer

Gustavson C, Wass C, Mansson JE, Blennow K, Forsman A, Anckarsater H, Nilsson T.
Platelet monoamine oxidase-B activity did not predict destructive personality traits or violent recidivism: A prospective study of forensic psychiatric examinees. Accepted for publication in Psychiarty Research.

Nilsson T, Bromander S, Anckarsäter R, Kristiansson K, Forsman A, Blennow K, Zetterberg H, Anckarsäter H, Wass C. Neurochemical characteristics co-vary with personality traits: Forensic psychiatric findings replicated in the general population.

Manuskript ännu ej accepterade för publikation

Wass C, Kallstrand J, Klamer D, Katsarogiannis E, Fejgin K, Pålsson E, Svensson L, Engel J, Rembeck B (Manuscript-a) L-lysine treatment cause normalization of altered sub-cortical acoustically elicited activity in individuals diagnosed with schizophrenia.

Wass C, Klamer D, Katsarogiannis E, Fejgin K, Pålsson E, Svensson L, Inga-Britt Bogren., Engel J, Rembeck B (Manuscript-b) L-lysine as adjunctive treatment in patients with schizophrenia: Results from a proof-of-concept study.

Bromander S, Anckarsäter R, Ahrén B, Kristiansson M, Blennow K, Zetterberg H, Holmäng A, Anckarsäter H, Wass C. Changes in cerebrospinal fluid insulin during non-neurological surgery.

Arbetsgivare Anställningsgrad BörjadeSlutade
Statligt - Universitet - Göteborgs universitet - Sahlgrenska akademin - Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi [2006 - ]
 100% 2005 2008
Statligt - Universitet - Göteborgs universitet - Sahlgrenska akademin - Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi [2006 - ]
 100% 2009

Teaching for medical students, dentist students, pharmacists, biomedical analysts:

Lectures: since 2005

“Pharmacology of the adrenal cortex”
“Pharmacology of depression and mania”

Demonstrations & Laboratory Practice:since 2005

“Monoaminergic mechanisms”
“Pharmacokinetics (computer lab)”
“Group seminars in basal pharmacology”

Supervising:since 2004

Bachelor of Science students (10-week projects)
Master thesis students (20-week projects

Work: Norsbrons treatment clinic for 1995-97
patients with Autism, Vålberg, Sweden

Organizing clinical studies including:

* Writing Institutional Review Board applications.
* Creating networks and translational cooperation
between preclinical and clinical institutions.
* Setting up and running the SR-HLAB™ system
in order to test sensory information processing
in human subjects.

Oral presentations:

C. Wass, E. Pålsson, K. Fejgin, D. Klamer, J.A. Engel, T. Archer, L. Svensson. Kväveoxid-medierade effekter av PCP på spatial inlärning. (Presented at the Swedish Society of Biological Psychiatry meeting, Särö, Sweden, 2005)

C. Wass, E. Pålsson, K. Fejgin, D. Klamer, J.A. Engel, T. Archer, L. Svensson. Schizophrenia-related working memory deficits in the rat are normalized by nitric oxide synthase inhibition. (Presented at the Scandinavian College of Neuropsychopharmacology, Marienlyst, Denmark, 2006)

Laboratory experience:

Animal handling (rats, mice)
Morris water maze
Radial arm maze
Ultrasonic vocalization measures
Neurodevelopmental models of schizophrenia
Brain dissection
Pre-pulse inhibition
Locomotor activity experiments
Stereotaxic surgery
In vivo brain microdialysis experiments
Cerebral microinjection experiments (in pups)
Data analysis and statistical evaluation of experimental data

Informationen är tillförlitlig | uppdaterad: 2012-05-08 av Caroline Wass |
Personkort för Caroline Wass, från ALF-medel Västra Götalandsregionen
http://www.fou.nu/is/alfgbg/user/html/9532